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Niacinamide: Board-Certified Tips for Healthier Skin
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Niacinamide: Board-Certified Tips for Healthier Skin

23 April 2025


Today, niacinamide has become one of the most popular skin care ingredients for many reasons. In this article, we’ll take a look at the various skin benefits of niacinamide, what’s in your serum, and how to use it, according to




reputable, board-certified dermatologists.



What is niacinamide? Niacinamide is a form of vitamin B3, a water-soluble vitamin that is essential for overall body and skin health. As nationally certified dermatologist Dr. Davin Lim explains, niacinamide is considered a very




flexible active ingredient explaining that it is actually one of the easiest skin care vitamins to use because it is paired with vitamin C A (also known as It has high tolerability and an extremely low frequency of side effects



compared to even vitamin C (retinol).




Niacinamide serums are a great way to incorporate the many skin benefits of niacinamide into your daily skin care routine because serums – due to their lightweight formula – can deliver high concentrations of active ingredients



into the skin to specifically target or treat specific skin problems.




What are the benefits of niacinamide for skin? According to nationally certified dermatologist Dr. Shereen Idriss, topical niacinamide can perform many different functions in the skin, such as:



Therefore, it is important to keep the skin intact and firmly connected through keratin in order to maintain the immune function of the skin and better protect us from external factors. Improves lipid barrier function:




Nicotinamide can also increase ceramide production.



Ceramides are lipids that act as intercellular “glue” to hold skin cells together, keeping skin soft and hydrated. Increased ceramide production allows the skin to retain its natural moisture, which can be helpful in treating




certain conditions such as eczema.



Anti-inflammatory effects: Nicotinamide has been shown to reduce the production of several mediators and molecules involved in the inflammatory process [1]. Therefore, it is beneficial for acne patients who have inflammatory




bumps and pimples.



In addition, niacinamide may help reduce redness, which may be beneficial for people with rosacea, as Dr. Lindane suggests. Regulates oil production: Niacinamide 2% has been shown to control the production and excretion of




sebum, which is responsible for facial shine and acne formation.



Helps even skin tone: There is evidence that nicotinamide may be an effective compound that inhibits the transfer of melanin granules (also called melanosomes) from melanocytes to keratinocytes.




Although niacinamide alone may not be as effective against hyperpigmentation, explains Dr. Shereene Idriss says it boosts the effects of other ingredients like vitamin C, kojic acid and arbutin to help achieve a more even skin



tone.




Anti-aging effects: Niacinamide has the potential to promote skin collagen synthesis and inhibit its breakdown, thereby providing firmness, improving surface texture, and smoothing fine lines and wrinkles. So what can



niacinamide be used for?




Due to its numerous proven biological functions in the skin, niacinamide may be suitable for all skin types to treat different skin concerns. Certified dermatologists use it for: Acne prone skin and oily skin.



What is the optimal application concentration? Now that you know its many benefits and uses, you might be thinking that the higher the concentration of nicotinamide in your serum, the better, right? We’re here to tell you that’s




not true.



Niacinamide serums are available in concentrations of 2% to 20%, with 10% being the most common. However, nationally board-certified dermatologist Dr. Jenny Liu points out that most of the benefits of niacinamide have been




demonstrated at lower concentrations of 2 to 5 percent, while at higher concentrations, no studies have shown actual benefits.



In fact, Dr. Shereene Idris points out that “more is not enough,” and serums above 5% (like those in a 10% formula) can cause irritation, inflammation, and breakouts—all skin problems you really want to treat.




In that order, most board-certified dermatologists recommend using a niacinamide serum with a concentration between 2% and 5%. Additionally, you can look for serums that already combine niacinamide with other ingredients to



minimize the number of products used to treat a specific skin concern, such as Dr. Shailene Idris recommends.




For these 10% serums, Dr. Shereene Idriss believes that when formulated with 1% zinc (such as regular niacinamide serum), the zinc acts as an anti-inflammatory agent, greatly reducing the inflammatory potential of niacinamide.


How to use niacinamide serum correctly? The great thing about niacinamide, says Dr. Davin Lim says it combines well with most skincare ingredients, like retinol and vitamin C. In this regard, niacinamide serum can be used with

other skin care products without any incompatibility.

– Should you use it in the morning or evening? It can be used in the morning and/or evening, but most people prefer to use the Niacinamide Serum at night, which is what Dr. Davin Lim recommends.

– How to use it? If you’re new to niacinamide serums, Dr. Shereene Idriss starts with using it once a day to see how your skin responds to this new product.

When it comes to your skin care routine, products should be used in a specific order. In a basic skin care routine, serum should be used after cleansing and before moisturizing (either morning or evening). Why in this order?

Nationally certified dermatologist Dr. Muneeb Shah divides skin care into three stages:

1. Cleanse: It’s important to remove dirt, sweat, oil, and impurities so that your skin remains clean and ready to reap the benefits of skin care products and active ingredients.

2. Treatment: This step is dedicated to using a serum rich in active ingredients that targets your skin’s specific concerns.

3. Protect: This step involves applying moisturizer to prevent moisture loss from the skin, followed by sunscreen (AM procedure) to protect the skin from UV rays. He explains that niacinamide works on the skin during the

treatment phase, before it is sealed with a layer of moisture. take away Niacinamide has been shown to be an excellent multifunctional active ingredient suitable for all skin types and, if well tolerated, can relieve a variety

of skin problems. While it’s worth the hype, it’s important to realize that concentration plays a key role, and dermatologists recommend choosing a serum with a concentration between 2% and 5% to get the most benefit from

niacinamide without the risk of an inflammatory reaction. Scientific evidence supports its effectiveness and safety.

DQH Can I use salicylic acid first and then vitamin C? It’s easy to create a skincare routine, but knowing how to use it is another thing entirely. In most cases, if you’re not getting the desired skin results, it could be due to the layering of conflicting ingredients. So, is it possible that salicylic acid and vitamin C are such ingredients? Or are these active ingredients the duo that’s been missing from your skincare routine? If you want answers, stick around because today we are going to explain the benefits of salicylic acid and vitamin C and how they can be used in your daily life. What are the benefits of salicylic acid for skin? Salicylic acid is one of the most commonly used beta hydroxy acids and is favored by many people with oily, acne-prone skin. This acid is derived from willow bark, and unlike its water-soluble relatives (called alpha-hydroxy acids), salicylic acid is oil-soluble, which means it can penetrate deeper into the lower layers of the skin. Once it reaches the lower layers, it can help unclog pores of excess sebum, dirt, bacteria, debris, and impurities. This results in clearer skin tones and greater definition. Not only does salicylic acid benefit the underlying layers, but the outer surface of the skin benefits as well. When applied to the skin, salicylic acid removes the buildup of dead skin cells. This is accomplished by breaking the bonds that hold dead cells to the surface. Over time, this can cause the complexion to look dull and prone to acne, blackheads, and other blemishes. If you’d like to learn more about salicylic acid and how it can improve your skin, check out this dedicated blog post from a beauty insider. What are the benefits of vitamin C for skin? Vitamin C is considered one of the most powerful antioxidants, which means it is very effective at fighting free radicals and preventing them from causing further skin damage. Examples of free radicals include pollution, central heating, UV rays and harsh climate. They attack proteins, fats and cell membranes as soon as they come into contact with the skin, causing signs of premature aging such as fine lines and wrinkles as well as hyperpigmentation, flaky patches of skin and loss of elasticity. Many people usually prefer to use vitamin C in their morning routine as this ingredient gives the complexion a radiant glow. You’ll also find that vitamin C can target areas of hyperpigmentation, plumping the skin and reducing the appearance of fine lines and wrinkles. The thing about vitamin C is that there are a lot of outdated studies going back to the 1950s that describe vitamin C as an unstable skin component. Thanks to improvements in modern technology, this is no longer the case as all products now contain a stable form of vitamin C. Visit The Beauty Insider to learn more about vitamin C. So please check out our blog post. Can I use salicylic acid first and then vitamin C? Yes, you absolutely can. In fact, it’s thought that using salicylic acid before using vitamin C ensures it penetrates faster and works faster. This is an efficient way to utilize two power sources, and the reason has to do with pH. For example, the skin’s natural pH is about 4.7, making it slightly acidic. Salicylic acid and vitamin C are also both acidic, and you’ll find that vitamin C is absorbed quickly into the skin. Therefore, using salicylic acid beforehand can increase the acidity of the skin and allow vitamin C to penetrate into the skin faster. While this is considered an effective way to combine two powerful ingredients, you need to be aware of your skin type and how it reacts to certain active ingredients. Even people with perfect, normal skin can experience skin sensitivity and irritation. Therefore, always consult a doctor or dermatologist before using any new products on your skin. It’s also important to follow skin application rules. In this case, you need to use the product correctly to ensure you get the best results for your skin. If you’re not sure what I mean, the basic rule for skin is to start with the thinnest consistency and work your way up to the thickest consistency. This prevents a barrier from forming on the surface, preventing other active ingredients from penetrating the skin. Can I use salicylic acid at night and vitamin C in the morning? Yes, absolutely, this is considered the most effective way to get returns without any adverse side effects. This is because there is enough time between applications to ensure that the skin’s pH levels return to balance. You’ll also find that Vitamin C is rich in antioxidants and is perfect for use in the morning to ensure your skin is protected and looking its healthiest. Due to the small size of salicylic acid molecules, it is an acid that is able to reach the deepest parts of the skin. While this is effective at keeping skin clear, it also increases the risk of irritation and photosensitivity. Therefore, many people prefer to use powerful BHAs in their evening routine without exposure to UV rays, pollution, or harsh weather. Warning: If you avoid using sunscreen every day, none of these ingredients will do what your skin needs. The combination of chemical peels and powerful ingredients increases the risk of further damage to the skin’s surface. Use SPF 50 every day to keep your skin protected and your lipid barrier healthy, even on cloudy days, keeping your skin in top condition.
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