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Sun-Safe Skincare: The Science of Polypodium Leucotomos
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Sun-Safe Skincare: The Science of Polypodium Leucotomos

11 May 2025



Skin Care Science: Polypodium Leucotomos Extract

Polypodium Leucotomos Extract (PLE)

As a dermatologist, I’m always interested in skin care ingredients that work in unique ways. Polypodium leucotomos is one of those ingredients. It is a tropical fern native to Central and South America, and has come under the spotlight for its skin benefits. What makes this ingredient so interesting to me is that its extract is almost exclusively used in oral supplements.

This fascinating plant isn’t your ordinary fern—it packs a powerful antioxidant punch against the harmful effects of sunlight, and can treat certain pigmentation conditions. In this comprehensive overview, we’ll delve deep into the origins, benefits, and uses of Polypodium leucotomos.

To find out which the best products for your skin type are, take the Baumann Skin Type Quiz for free today with the button below!

What is Polypodium Leucotomos?

Polypodium leucotomos extract, often abbreviated as PLE, is derived from a fern that thrives in the tropical regions of the Americas. Its use dates back to traditional cultures in these areas, where it was used for its health-promoting properties. PLE is rich in potent antioxidants, such as phenolic compounds including caffeic, ferulic, and chlorogenic acids. (2) These components give PLE its ability to ward off harmful free radicals, protect against ultraviolet (UV) radiation, and support skin health in various ways.

Where Does Polypodium Leucotomos Come From?

The Polypodium leucotomos fern grows predominantly in Central and South America, thriving in humid, shaded areas. Historically, it was used by indigenous peoples for its protective properties against sun damage and its general health benefits. Today, the extracts of this fern are studied and utilized worldwide, thanks to modern cultivation and extraction techniques that have made its benefits accessible to a global audience.

Benefits of Polypodium Leucotomos

The benefits of Polypodium leucotomos are primarily linked to its photoprotective and antioxidant properties. Studies show that PLE can significantly reduce the damage caused by UV rays, including reducing the risk of sunburn, preventing redness, and minimizing DNA damage that can lead to skin cancer. (3) Additionally, PLE’s anti-inflammatory and immuno-protective properties make it a valuable supplement for maintaining skin health and combating photoaging. Some studies have even found that Polypodium leucotomos is suitable for certain pigmentation conditions such as melasma, vitiligo, and post-inflammatory hyperpigmentation. (1-10)

Here are some of the best skin care products with polypodium leucotomos:

Side-effects/Risks of Polypodium Leucotomos

Polypodium leucotomos extract is generally well-tolerated by most individuals, with few reported side effects. Some people may experience stomach upset or skin rashes, particularly if you take too many of the pills. It is always advisable to start with a lower dose to assess tolerance and consult with a healthcare provider before starting any new supplement, especially for those with existing health conditions or those taking other medications.

“Sunscreen pills are meant to be used in addition to sunblock and sun protective clothing”

How Do Sunscreen Pills Work?

Sunscreen pills containing PLE work by enhancing the body’s natural defense mechanisms against UV radiation. When ingested, PLE increases the levels of antioxidants in the skin, which can neutralize the harmful free radicals generated by UV exposure. Additionally, PLE modulates the expression of genes involved in skin inflammation and cellular response to sunlight, providing a systemic form of photoprotection. (5,6)

PLE does not provide enough photoprotection when used alone and should always be combined with sunscreen and sun protective clothing.

Comparing Polypodium Leucotomos with Other Sunscreen Ingredients

When it comes to protecting your skin from the harmful effects of the sun, there are a variety of sunscreen ingredients and products to choose from. Each has its unique benefits and uses, and understanding these can help you make informed decisions about your skin health. Here, we’ll compare Polypodium leucotomos (PLE) with other common sunscreen ingredients to help you gauge its effectiveness and suitability for your skin care needs. Before we get into direct comparisons, it is important to mention that using a topical sunscreen is important, even if you also take sunscreen pills. Topical sunscreens that directly interfere with solar radiation at the surface are always the best bet for sun protection. That’s why these sunscreen pills are called “supplements.”

Polypodium leucotomos Vs. Chemical Sunscreens

Chemical Sunscreens: These sunscreens, containing active ingredients like avobenzone, oxybenzone, octinoxate, and others, work by absorbing UV radiation through their chemical bonds. As the sunlight hits the skin, these compounds transform UV rays into non-damaging heat which is then released from the skin.

Polypodium Leucotomos: Unlike chemical sunscreens that absorb UV light, PLE acts mainly by neutralizing free radicals and reducing oxidative stress within the skin, which is often a result of UV exposure. This means PLE helps minimize the broader cellular damage caused by sunlight, not just prevent sunburn.

Key Differences:

Mechanism of Action: Chemical sunscreens absorb UV rays while Polypodium leucotomos provides an internal antioxidant defense, combating the free radicals generated by UV exposure.

Application: Chemical sunscreens are applied topically and need reapplication every few hours, especially after swimming or sweating. Polypodium leucotomos, taken orally, offers a form of internal sun protection that complements topical sunscreens, especially in hard-to-reach areas.

Irritation Potential: Some chemical sunscreens can irritate sensitive skin or cause allergic reactions. Polypodium leucotomos is generally well-tolerated, with fewer reported side effects, making it suitable for people with sensitive skin.

Polypodium leucotomos Vs. Physical (Mineral) Sunscreens

Physical Sunscreens: Ingredients like zinc oxide and titanium dioxide are physical blockers that sit on the skin’s surface. They reflect and scatter UV radiation before it penetrates the skin. Physical sunscreens are often recommended for those with sensitive skin as they are less likely to cause irritation.

Polypodium Leucotomos: While physical sunscreens protect the skin by forming a barrier on its surface, PLE works from the inside, enhancing the skin’s resilience against UV-induced damage through its antioxidant properties.

Key Differences:

Visibility: Physical sunscreens can leave a white cast on the skin, which some users might find unappealing, whereas Polypodium leucotomos, being an oral supplement, does not affect the appearance.

Protection Spectrum: Physical sunscreens offer broad-spectrum protection against both UVA and UVB rays. Polypodium leucotomos protection complements this by addressing the oxidative stress caused by these rays.

Ease of Use: Physical sunscreens require diligent application and can be washed off, requiring reapplication. Polypodium leucotomos offers continuous protection throughout the day with a simple oral dose.

Mineral sunscreens are generally regarded as the best, and I agree in most cases. Here are some of the best mineral sunscreens:

Polypodium leucotomos Vs. Synthetic Antioxidant Sunscreens

Synthetic Antioxidant Sunscreens: These are newer formulations that incorporate antioxidants like Vitamins C and E into traditional sunscreen products to provide added protection against photoaging and free radicals.

Polypodium Leucotomos: PLE naturally contains several potent antioxidants, which provide a less significant amount of protection against free radical damage than most synthetic antioxidants used in sunscreens.

Key Differences:

Antioxidant Profile: PLE provides a unique blend of natural antioxidants that work synergistically to protect skin cells from UV-induced damage, whereas synthetic antioxidants may not always cover as broad a spectrum of oxidative damage, even though they are generally more effective.

Longevity of Protection: The antioxidants in PLE are part of your diet and can provide a longer-lasting effect throughout the body, whereas topical antioxidants may degrade more quickly on the skin surface.

Conclusion

Polypodium leucotomos stands out as a natural and effective solution for those seeking to protect their skin from the inside out. Whether you are an avid outdoor enthusiast or someone looking to add an extra layer of protection against photoaging, PLE offers a promising addition to your skincare regimen. Remember, while polypodium leucotomos can significantly boost your skin’s defense against sunlight, it should complement, not replace, topical sunscreens and protective clothing. For a holistic approach to skin health, consider incorporating Polypodium leucotomos into your daily routine and always consult with a healthcare provider to ensure it’s right for you.

To make sure you only ever buy the right skin care products for your skin type, take the Baumann Skin Type Quiz for free today with the button below!

DQH Knowledge drop: In your 20s, your skin cell turnover decreases. (Cell turnover is a key component in keeping your skin youthful.) You know what else slows down? Your collagen production. Starting in your 20s, collagen decreases by about 1 percent per year. Should you want to prevent fine lines and wrinkles, start by eliminating behaviors that contribute to premature aging. “If it’s bad for you, it’s bad for your skin,” says dermatologist Michel Somenek. “Cigarette smoking reduces blood flow to the skin and causes premature wrinkling and a dull skin texture. Making the repeated pursed motion to inhale can also cause smoker’s lines. Alcohol and recreational drugs are toxins for the skin that damage its cellular structure and DNA,” Somenek tells us. “The faster you eliminate vices while you are young, the better chance your skin and body have to recuperate.” Also, adopting an anti-aging routine in your 20s is key. After all, the best offense is a good defense. We spoke to Somenek and experts Joshua Ross and Audrey Kunin to find out more. Keep reading for the best anti-aging products for your 20s, according to skincare professionals. Sunscreen “We all know that the sun is the number one cause of skin aging and starting the prevention in your 20s is very important,” Ross says. “The majority of your sun damage won’t start to appear until you’re in your 30s, so don’t wait until you see it surface or you’ll be behind the curve. Stay ahead of it with a good-quality zinc-based sunscreen worn daily.” Farmacy Green Defense Daily Mineral Sunscreen An invisible sunscreen with SPF 30, plus botanical extracts meant to protect skin with tons of antioxidants. Bonus: It’s clean and fine to use under makeup. Bareminerals Complexion Rescue™ Tinted Moisturizer Broad Spectrum SPF 30 Although we recommend you use your SPF and moisturizer separately, we also understand moments when you don’t have time or energy for that extra step. For those times, this bareMinerals moisturizer is a great thing to have on hand. Vitamin C Serum “A great introduction to anti-aging is to start with a vitamin C serum in your morning skincare routine,” Ross says. “It’s a powerful antioxidant that will neutralize free radicals and brighten the skin.” He adds that it’s a great way to counteract the effects of the sun’s harmful rays, which, as previously mentioned, are among the biggest causes of premature aging. Drunk Elephant C-Firma™ Vitamin C Day Serum The Drunk Elephant C-Firma is a lightweight serum that promises to give skin a glow by combining the brightening powers of vitamin C with ferulic acid, l-ascorbic acid, and vitamin E. The included sodium hyaluronate is meant to replace hydration loss, so you shouldn’t have to deal with any irritation. Sunday Riley C.E.O. Rapid Flash Brightening Serum This potent serum is jam-packed with vitamin C (15 percent, to be exact), which means it’s a potential superstar at both brightening skin and dousing it in antioxidants. Peptides Using peptides on your skin has many benefits, says Somenek. “The skin barrier is what defends the body against pollution, UV rays, bacteria, and toxins. It can be damaged by several everyday factors. Using topical peptides aids in building a stronger barrier,” he says. “Peptides comprise elastic fibers, which are a type of protein. These fibers help to make skin appear taut and firm. Peptides can also help repair damaged skin, relieve inflammation, and even out skin tone. Some peptides can kill acne-causing bacteria that is common in 20-somethings.” Kunin agrees, saying, “Peptides are an excellent entry point for supporting collagen.” She recommends looking for face and eye treatments that contain these collagen-boosting powerhouses. Charlotte Tilbury Magic Eye Rescue Cream This Charlotte Tilbury super-emollient eye cream has a base of coconut oil and shea butter (read: it’s incredibly hydrating). Botanicals plus peptides are meant to help reduce dark circles and boost collagen, respectively. This creamy moisturizer serves up potent collagen-boosting peptides and pycnogenol, and antioxidant-rich vitamin C. “Instead of sitting on top of the skin, peptides penetrate the outer layer so they go deep. The ‘signals’ they send tell the cells to produce elastin and collagen, which are needed for youthful-looking skin,” explains Somenek. At-Home Peel Pads Remember that skin cell turnover fiasco we talked about earlier? One way to help support it is by exfoliating. “Exfoliation is important to help keep skin fresh and luminous,” Kunin says. She recommends using at-home peel pads as an easy and effective way to exfoliate. “The goal in your 20s is to fight the slowing pace of cell turnover. It is wise to use products that gently exfoliate, yet still remove oil and other impurities. Products that have Alpha Hydroxy Acids (AHA) or Beta Hydroxy Acids (BHA) are a good choice.” According to Somenek, you should only exfoliate two to three times a week. “People of all ages are guilty of over-exfoliating and that can be too much of a good thing,” he says. Dermadoctor Kakadu C Intensive Vitamin C Peel Pad A few swipes of this Derma Doctor powerful peel pad promise to leave your skin glowing and smooth, thanks to the seven (yes, seven) types of chemical exfoliants, including AHA and BHA. It also contains vitamin C via Kakadu plum extract for added brightening and antioxidant protection. KEY INGREDIENTS Kakadu plum extract is sourced from the Kakadu plum, a fruit grown in northern Australia. It contains vitamin C, which restores the skin’s natural barrier, increases collagen production, and soothes irritation. Dr. Dennis Gross Skincare Alpha Beta® Universal Daily Peel Pads These are the gold standard of peel pads, with a cult following and over 900 five-star reviews on Sephora. They’re easy to use and contain a blend of anti-aging exfoliating acids. Emollient Night Cream “In your 20s, you need to start upping the hydration in your skincare routine. You may have been cautious of over-moisturizing because of acne in your teens, but as you enter your 20s, your skin transitions and becomes drier,” Ross says. “I recommend an emollient night cream added into your evening skincare regimen.” “Twenty-somethings need to make sure that they are not using creams that will clog their pores and cause excess oil production,” says Somenek. Opt for non-comedogenic products. Cerave Skin Renewing Night Cream One great choice is the CeraVe Skin Renewing Night Cream, which is a non-comedogenic night cream that leaves skin soft and glowy. It combines the moisturizing powers of ceramides and hyaluronic acid. RoC Retinol Correxion Max Hydration Creme “The best night cream ingredients contain retinol, benzoyl peroxide, and/or salicylic acid or hyaluronic acid. The goal is to moisturize, yet remove excess oil,” says Somenek. This Roc Retinol Correxion cream fits the bill as it contains both hyaluronic acid and retinol so it promises to moisturize while also being non-comedogenic.
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