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The Power of Squalane for Skin and Hair Health
Skin Care

The Power of Squalane for Skin and Hair Health

30 May 2025


The Power of Squalene and Squalane in Skin and Hair Care: What You Need to Know

Believe it or not, our bodies have very smart systems designed to protect us from environmental damage.

These include defense mechanisms against air pollution, prolonged exposure to the sun, and even mechanisms that reduce the risk of cancer.

One of our most fascinating and complex protection systems is our skin – it not only protects our bodies, but also plays an important role in immune defense, hydration, and temperature regulation.

At the heart of this natural defense system is a compound that was once overlooked but has since become a star in the world of skincare and cosmetics: squalene and its more stable counterpart, squalane.

What is squalene and why is it so important?

Squalene is a natural lipid produced by plants and animals and is also a component of human sebum (the oily substance secreted by the sebaceous glands in the skin).

This oil is important for soft, smooth, and elastic skin.

In human biology, squalene acts as a natural emollient, lubricant, and antioxidant, protecting the skin from environmental pollutants and oxidative stress caused by UV rays.

Squalene is not only useful, but also essential for skin health. Unfortunately, like many biological processes, the body’s own production of squalene decreases with age.

This decline leads to common signs of aging, such as dry skin, fine lines, and a weakened skin barrier.

The Rise of Squalane: Skincare’s Best Kept Secret

As natural, science-based skincare products grow in popularity, squalane, the stable, hydrogenated form of squalene, is taking the spotlight.

Unlike squalene, which oxidizes quickly and has a short shelf life, squalane is shelf-stable and suitable for use in a wide range of cosmetic formulations.

It’s no surprise that beauty influencers, dermatologists, and the wellness community have discovered squalane. On platforms like TikTok, hashtags like “#squalane” have garnered millions of views.

Users report refreshed skin and a streamlined skincare routine after using squalane serums, creams, and oils.

Where Does Squalene Come From? Is It Sustainable?

Historically, one of the most concentrated sources of squalene was found in the livers of deep-sea sharks—a practice that has raised ethical and environmental concerns.

Today, squalene (and squalane) in cosmetics is mostly derived from plants, such as olives, rice bran, sugar cane, and amaranth seeds. This makes it a more sustainable and cruelty-free choice.

Before buying skincare products, it’s always a good idea to check the origin of the ingredients.

Look for labels that say “plant-based” or “vegan squalane,” especially if animal welfare and environmental sustainability are important to you.

Squalene vs. Squalane: What’s the Real Difference?

Despite their nearly identical names, squalene and squalane are chemically different:

Squalene (with an “e”) is a naturally occurring unsaturated compound found in our skin and from animal and plant sources.

It’s very beneficial, but also very unstable and easily oxidizes when exposed to air or light.

Squalane (with an “a”) is the hydrogenated form of squalene. Hydrogenation converts the double bonds in squalene into single bonds.

This makes it more stable, non-oxidizing, and suitable for long-term storage and cosmetic formulations.

Essentially, squalane retains all the nourishing benefits of squalene without the drawbacks of rapid degradation.

6 Significant Benefits of Squalane for Skin and Hair

1. Prevents Premature Skin Aging

Squalane is often hailed as an effective anti-aging agent. Because it closely resembles the skin’s natural oils, it blends seamlessly into the lipid layer of the epidermis.

This not only moisturizes the skin, but also reduces fine lines, wrinkles, and dullness.

Squalane regenerates the skin’s moisture, making it appear younger and more radiant. Many users report significant improvements in skin texture and elasticity after regular use of squalane products.

💡 Tip: Use a night cream with vegan squalane and hyaluronic acid to retain moisture while you sleep. Look for formulas with glacial glycoproteins to promote skin regeneration.

2. Mimics the Skin’s Natural Oils

Because squalane has a biomimetic effect – i.e. it mimics the body’s natural lipids – it works well for almost all skin types, even sensitive and acne-prone skin.

It strengthens the skin barrier, reduces transepidermal water loss, and protects against UV rays, toxins, and allergens.

One of the hidden benefits of squalane is its ability to enhance sun protection, giving the skin an extra line of defense against damaging carcinogens.

3. Deep Hydration

As we age, the body’s own production of squalene slows significantly. The result is drier, less elastic skin. Restoring this lipid through skincare helps restore the natural moisture barrier.

Serums and creams containing squalane have a silky-soft texture that doesn’t feel greasy or heavy. They penetrate deep into the dermis and retain moisture for hours.

💡 Tip: Try a facial oil like Dreamy Glow Drops, which combines squalane with other antioxidants to leave skin soft, hydrated, and glowy.

4. Strengthens and Nourishes Hair

The benefits of squalane extend far beyond the skin. Applied to hair, squalane oil acts as a lightweight, non-greasy moisturizer that protects against heat, pollution, and UV rays.

It can help repair split ends, restore shine and reduce frizz. Unlike heavier oils that can clog follicles or weigh down fine hair, squalane absorbs quickly and leaves behind a soft, natural-looking shine.

💡 How to Use: Warm a few drops between palms and apply to wet or dry hair. Rinse after 20 minutes for an intensive treatment, or leave on skin for a subtle glow.

5. Non-comedogenic: Won’t clog pores

One of squalane’s most notable properties is its non-comedogenic benefits. Unlike mineral oils and strong occlusives, squalane allows the skin to breathe.

It doesn’t clog pores, making it perfect for those with oily or acne-prone skin.

Squalane also has a soothing effect on active acne, reducing redness, relieving irritation, and speeding up regeneration.

💡 Products to try: Complement your skincare routine with a deep cleansing product containing squalane—it exfoliates, removes impurities, and hydrates.

6. Improves the overall appearance of your skin

Squalane can visibly improve skin tone, texture, and clarity. Regular use helps:

Lightens dark spots and hyperpigmentation

Reduces acne scars

Relieves eczema and rosacea

Reduces inflammation and redness

Its antioxidant properties help neutralize free radicals, protect the skin from oxidative stress, and slow the breakdown of collagen and elastin.

Who should use squalane?

Due to its gentle, hypoallergenic properties, squalane is suitable for almost everyone. It is safe for:

Dry and sensitive skin

Oily and acne-prone skin

Mature skin seeking anti-aging solutions

People undergoing cosmetic treatments such as chemical peels or laser therapy

Infants and pregnant women can also safely use plant-based squalane to soften the skin and repair the skin barrier. However, we always recommend consulting your doctor.

How to Incorporate Squalane into Your Routine

It’s easy to incorporate squalane into your skin and hair care routine:

Use squalane oil as a serum after cleansing and before moisturizing.

Mix a drop into foundation or BB cream for a dewy finish.

Apply to the hair shaft and ends before heat styling.

Use it as a night cream to restore moisture while you sleep.

Look for cleansers, creams, or masks that have squalane as a base ingredient.

Final Thoughts: Nature’s Answer to Modern Skincare

Squalane has truly earned its place in the spotlight from a relatively unknown compound to a multi-functional skincare superhero.

It delivers the nourishment of a rich cream, the lightweight feel of a serum, and the protection of natural antioxidants—all rolled into one elegant solution.

Whether you’re combating dryness, reducing signs of aging, caring for damaged hair, or looking for a reliable moisturizer that won’t clog your pores, squalane is a valuable addition to your skincare routine.

The next time you check a product label, remember: Squalane may be just the transformative ingredient your skin (and hair) has been waiting for.

DQH Knowledge drop: In your 20s, your skin cell turnover decreases. (Cell turnover is a key component in keeping your skin youthful.) You know what else slows down? Your collagen production. Starting in your 20s, collagen decreases by about 1 percent per year. Should you want to prevent fine lines and wrinkles, start by eliminating behaviors that contribute to premature aging. “If it’s bad for you, it’s bad for your skin,” says dermatologist Michel Somenek. “Cigarette smoking reduces blood flow to the skin and causes premature wrinkling and a dull skin texture. Making the repeated pursed motion to inhale can also cause smoker’s lines. Alcohol and recreational drugs are toxins for the skin that damage its cellular structure and DNA,” Somenek tells us. “The faster you eliminate vices while you are young, the better chance your skin and body have to recuperate.” Also, adopting an anti-aging routine in your 20s is key. After all, the best offense is a good defense. We spoke to Somenek and experts Joshua Ross and Audrey Kunin to find out more. Keep reading for the best anti-aging products for your 20s, according to skincare professionals. Sunscreen “We all know that the sun is the number one cause of skin aging and starting the prevention in your 20s is very important,” Ross says. “The majority of your sun damage won’t start to appear until you’re in your 30s, so don’t wait until you see it surface or you’ll be behind the curve. Stay ahead of it with a good-quality zinc-based sunscreen worn daily.” Farmacy Green Defense Daily Mineral Sunscreen An invisible sunscreen with SPF 30, plus botanical extracts meant to protect skin with tons of antioxidants. Bonus: It’s clean and fine to use under makeup. Bareminerals Complexion Rescue™ Tinted Moisturizer Broad Spectrum SPF 30 Although we recommend you use your SPF and moisturizer separately, we also understand moments when you don’t have time or energy for that extra step. For those times, this bareMinerals moisturizer is a great thing to have on hand. Vitamin C Serum “A great introduction to anti-aging is to start with a vitamin C serum in your morning skincare routine,” Ross says. “It’s a powerful antioxidant that will neutralize free radicals and brighten the skin.” He adds that it’s a great way to counteract the effects of the sun’s harmful rays, which, as previously mentioned, are among the biggest causes of premature aging. Drunk Elephant C-Firma™ Vitamin C Day Serum The Drunk Elephant C-Firma is a lightweight serum that promises to give skin a glow by combining the brightening powers of vitamin C with ferulic acid, l-ascorbic acid, and vitamin E. The included sodium hyaluronate is meant to replace hydration loss, so you shouldn’t have to deal with any irritation. Sunday Riley C.E.O. Rapid Flash Brightening Serum This potent serum is jam-packed with vitamin C (15 percent, to be exact), which means it’s a potential superstar at both brightening skin and dousing it in antioxidants. Peptides Using peptides on your skin has many benefits, says Somenek. “The skin barrier is what defends the body against pollution, UV rays, bacteria, and toxins. It can be damaged by several everyday factors. Using topical peptides aids in building a stronger barrier,” he says. “Peptides comprise elastic fibers, which are a type of protein. These fibers help to make skin appear taut and firm. Peptides can also help repair damaged skin, relieve inflammation, and even out skin tone. Some peptides can kill acne-causing bacteria that is common in 20-somethings.” Kunin agrees, saying, “Peptides are an excellent entry point for supporting collagen.” She recommends looking for face and eye treatments that contain these collagen-boosting powerhouses. Charlotte Tilbury Magic Eye Rescue Cream This Charlotte Tilbury super-emollient eye cream has a base of coconut oil and shea butter (read: it’s incredibly hydrating). Botanicals plus peptides are meant to help reduce dark circles and boost collagen, respectively. This creamy moisturizer serves up potent collagen-boosting peptides and pycnogenol, and antioxidant-rich vitamin C. “Instead of sitting on top of the skin, peptides penetrate the outer layer so they go deep. The ‘signals’ they send tell the cells to produce elastin and collagen, which are needed for youthful-looking skin,” explains Somenek. At-Home Peel Pads Remember that skin cell turnover fiasco we talked about earlier? One way to help support it is by exfoliating. “Exfoliation is important to help keep skin fresh and luminous,” Kunin says. She recommends using at-home peel pads as an easy and effective way to exfoliate. “The goal in your 20s is to fight the slowing pace of cell turnover. It is wise to use products that gently exfoliate, yet still remove oil and other impurities. Products that have Alpha Hydroxy Acids (AHA) or Beta Hydroxy Acids (BHA) are a good choice.” According to Somenek, you should only exfoliate two to three times a week. “People of all ages are guilty of over-exfoliating and that can be too much of a good thing,” he says. Dermadoctor Kakadu C Intensive Vitamin C Peel Pad A few swipes of this Derma Doctor powerful peel pad promise to leave your skin glowing and smooth, thanks to the seven (yes, seven) types of chemical exfoliants, including AHA and BHA. It also contains vitamin C via Kakadu plum extract for added brightening and antioxidant protection. KEY INGREDIENTS Kakadu plum extract is sourced from the Kakadu plum, a fruit grown in northern Australia. It contains vitamin C, which restores the skin’s natural barrier, increases collagen production, and soothes irritation. Dr. Dennis Gross Skincare Alpha Beta® Universal Daily Peel Pads These are the gold standard of peel pads, with a cult following and over 900 five-star reviews on Sephora. They’re easy to use and contain a blend of anti-aging exfoliating acids. Emollient Night Cream “In your 20s, you need to start upping the hydration in your skincare routine. You may have been cautious of over-moisturizing because of acne in your teens, but as you enter your 20s, your skin transitions and becomes drier,” Ross says. “I recommend an emollient night cream added into your evening skincare regimen.” “Twenty-somethings need to make sure that they are not using creams that will clog their pores and cause excess oil production,” says Somenek. Opt for non-comedogenic products. Cerave Skin Renewing Night Cream One great choice is the CeraVe Skin Renewing Night Cream, which is a non-comedogenic night cream that leaves skin soft and glowy. It combines the moisturizing powers of ceramides and hyaluronic acid. RoC Retinol Correxion Max Hydration Creme “The best night cream ingredients contain retinol, benzoyl peroxide, and/or salicylic acid or hyaluronic acid. The goal is to moisturize, yet remove excess oil,” says Somenek. This Roc Retinol Correxion cream fits the bill as it contains both hyaluronic acid and retinol so it promises to moisturize while also being non-comedogenic.
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