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What Is the Skin Barrier? Functions, Issues, and Fixes
Skin Care

What Is the Skin Barrier? Functions, Issues, and Fixes

7 June 2025


What Is the Skin Barrier? Function, Signs of Damage, and How to Care for Yours

Want to know the first step in addressing any skin concern? According to TikTok: Repair your skin barrier first.

A term you used to hear only from your dermatologist during an appointment is now bandied about in casual conversation. Today, #skinbarrier has 5.2 billion views and counting on TikTok.

What Is the Skin Barrier, and How Does It Work?

The skin barrier is the outermost layer of the skin. Skin consists of three layers: the epidermis, the dermis, and the hypodermis, per Cleveland Clinic.

The epidermis is the top layer of skin, and the very outermost layer of the epidermis is called the stratum corneum.

“When we talk about the skin barrier, we’re referring to the stratum corneum,” says Abigail Waldman, MD, an assistant professor at Harvard Medical School and the clinical director of the Mohs

and dermatologic surgery center at Brigham and Women’s Hospital in Boston.

The stratum corneum, Dr. Waldman explains, functions like a brick wall around the skin and is made up of keratinocytes that are arranged like flat bricks combined to create a shield.

In the “mortar” are proteins and lipids to keep those bricks together.

What Is the Purpose of the Skin Barrier?

To put it simply, the skin barrier prevents things from escaping (such as moisture) while also preventing things from getting into your skin that you don’t want (allergens and viruses).

Here are three main functions of your skin barrier.

Keeps Skin Moisturized

The skin barrier helps your skin retain water so it’s supple and properly hydrated, notes Harvard Health Publishing. Dry skin, as a result, can be flaky and more prone to irritation and itch.

What’s more, well-moisturized skin appears plumper, which counteracts signs of premature aging, notes the American Academy of Dermatology.

Plays a Role in Immunity

Your skin plays a critical role in your health, and is your body’s first-line defense against things that can make you sick.

“When the skin barrier is compromised, it can increase the risk of infection, allergic reaction, irritation, itching, and pain,” says Lauren Ploch, MD, a board-certified dermatologist in Augusta, Georgia.

Protects Against UV Radiation

The outermost layer of skin, called the stratum corneum, provides the first source of protection against the sun’s damaging ultraviolet radiation, research has shown.

Once UV rays penetrate skin, the damage can trigger redness, signs of premature skin aging (wrinkles, discoloration), as well as skin cancers basal cell carcinoma, squamous cell carcinoma, and melanoma.

Unfortunately, UV rays also break down the skin’s barrier.

What Causes Damage to the Skin Barrier?

Fortunately or unfortunately, your skin isn’t made of steel, and Dr. Ploch says many things in the environment can compromise its integrity. These threats include:

Irritating skin-care products

Excessive water exposure

Weather changes (cold, wind, dry heat)

Irritants

Allergens

Trauma (cuts, burns, scrapes)

UV rays

Overexfoliation

In addition, a couple of factors that are out of your control can contribute to a compromised barrier, Waldman says:

Genetics can drive conditions that run in families, like eczema, says Waldman. Atopic dermatitis is one type of eczema. “Atopic dermatitis is a breakdown, or deficit, of the stratum corneum,” Waldman says.

This allows water to escape and allows irritants on the outside to enter the skin.

Aging causes structural changes in skin that lead to water loss, dehydration, and skin thinning, study in the November 2019 Immunology found.

Signs and Symptoms of Skin Barrier Damage

Your skin will tell you when something’s wrong. “Your skin can become red, itchy or dry and flaky [or some combination].

These are all signs that the skin barrier is damaged,” says Carmen Castilla, MD, a board-certified dermatologist in New York City.

How to Protect and Repair Your Skin Barrier

Moisturize Regularly

Your first must-do: Keep your skin well hydrated. “Dry skin is compromised skin,” says Ploch.

Choose skin moisturizers that have hydrating ingredients and can keep the skin barrier intact (or repair it when necessary). Top ingredients include hyaluronic acid, ceramides, and glycerin.

More on those below.

Another option, says Waldman, is to apply a product on skin that will mimic the stratum corneum.

“An ointment, like Vaseline or Aquaphor, will create a bubble around skin that mimics your natural skin and keeps water from escaping,” she says.

“This is one of the most effective, cheap, and easy ways to repair the skin barrier.” The downside is these products can feel thick and greasy, which many people don’t enjoy.

Choose the products based on the needs of your skin, as well as those you want to use regularly.

Choose a Gentle Cleanser

You may be surprised to hear that commonly used soaps can strip the skin of much-needed moisture and compromise its barrier, says Castilla. Choosing the right face cleanser for your skin type is key. “If you have drier skin, use a cream-based cleanser; for oilier skin, go for a foaming cleanser, which will remove some oil but not strip it altogether,” she says.

Also cleanse with lukewarm water, as hot water can also remove oil.

Apply Retinoids With a Light Hand

Retinoids, which are vitamin A derivatives, are used for stimulating collagen to plump up fine lines and wrinkles, as well as increase skin cell turnover, which can lighten discolorations and fight acne.

When using retinoids, especially for the first time, be aware that they’ll dry out the skin and cause some irritation.

If you have drier skin, Castilla recommends applying a retinoid once a week; oilier skin types may be able to tolerate application three times per week.

Keep in mind that what your skin can handle will also depend on the seasons.

Summer, with its humidity, may allow you to apply retinoids or other active ingredients that exfoliate the skin more often without causing irritation.

In the wintertime, you may find that the drier indoor and outdoor air means you need to scale back your retinoid.

Soothe Skin With Colloidal Oatmeal

If skin is already red and inflamed, Castilla recommends smoothing on a moisturizer that contains colloidal oatmeal.

Research shows that colloidal oats reinforce the skin barrier’s integrity and regulate oil production in the skin, among other functions, which has been shown to improve skin hydration.

(The study was done by the Johnson & Johnson Skin Research Center. The brand makes products, such as lotions, with oatmeal as an active ingredient.)

Colloidal oatmeal is also commonly used to relieve itching from eczema, according to the National Eczema Association.

Get Serious About Sunscreen

Finally, apply sunscreen every day, even when it’s cloudy outdoors, to protect your skin from damaging ultraviolet rays, Castilla recommends. Choose an SPF 30 or higher. A facial moisturizer with an SPF 30 is suitable for regular day-to-day use, but if you’re spending a lot of time outside sweating or going in the pool or beach, apply a sunscreen that’s designed for sport or swimming.

The Best and Worst Types of Products and Ingredients for Your Skin Barrier

Give your skin much-needed TLC by incorporating skin barrier-friendly ingredients and avoiding the top culprits that cause damage.

Best: Hyaluronic Acid (HA)

HA is a humectant, which means it attracts water from the environment to hydrate and plump skin, per research published in the August 2021 Dermatology and Therapy.

Hyaluronic acid (HA) is naturally found in the body, with one-third being found in the skin. One cool thing about HA? It can hold more than one thousand times its weight in water, notes Harvard Health Publishing.

Worst: Alcohol

If you review the ingredients of common toners and astringents, as well as a variety of other products, you’ll commonly find alcohol listed.

Alcohol is designed to strip oils from skin, but you need these to keep your skin barrier intact, says Castilla. Read the label on your products to make sure they’re alcohol-free.

Best: Ceramides

Ceramides make up “the most abundant lipid in the outermost layer of the skin barrier,” says Ploch, adding that amounts in the skin naturally decline with age.

Reaching for a cream with ceramides will naturally replace what your skin is lacking.

Worst: Scrubs

These products strip the skin’s outer layer of the oil it needs to stay moisturized, says Waldman.

Best: Glycerin

This ingredient is a top-notch moisturizer that helps maintain the skin’s integrity, according to a review of studies on aging adults in the March 2020 International Journal of Nursing Studies.

Worst: Basic Soaps

Soaps such as bar or liquid soaps designed for the hands and body should not be used on the face, as they are too harsh for its thinner skin, says Waldman.

Summary

Your skin barrier is an important part of your skin and body’s overall health. Maintaining your skin barrier’s integrity protects skin against moisture loss, environmental irritants, and damaging UV rays.

A compromised barrier — which can cause redness, dryness, and flakiness — may allow pathogens, irritants, and allergens to seep in.

You can care for your skin barrier with the right soap or cleanser, generous moisturization, and regular use of sunscreen.

DQH Can I use salicylic acid first and then vitamin C? It’s easy to create a skincare routine, but knowing how to use it is another thing entirely. In most cases, if you’re not getting the desired skin results, it could be due to the layering of conflicting ingredients. So, is it possible that salicylic acid and vitamin C are such ingredients? Or are these active ingredients the duo that’s been missing from your skincare routine? If you want answers, stick around because today we are going to explain the benefits of salicylic acid and vitamin C and how they can be used in your daily life. What are the benefits of salicylic acid for skin? Salicylic acid is one of the most commonly used beta hydroxy acids and is favored by many people with oily, acne-prone skin. This acid is derived from willow bark, and unlike its water-soluble relatives (called alpha-hydroxy acids), salicylic acid is oil-soluble, which means it can penetrate deeper into the lower layers of the skin. Once it reaches the lower layers, it can help unclog pores of excess sebum, dirt, bacteria, debris, and impurities. This results in clearer skin tones and greater definition. Not only does salicylic acid benefit the underlying layers, but the outer surface of the skin benefits as well. When applied to the skin, salicylic acid removes the buildup of dead skin cells. This is accomplished by breaking the bonds that hold dead cells to the surface. Over time, this can cause the complexion to look dull and prone to acne, blackheads, and other blemishes. If you’d like to learn more about salicylic acid and how it can improve your skin, check out this dedicated blog post from a beauty insider. What are the benefits of vitamin C for skin? Vitamin C is considered one of the most powerful antioxidants, which means it is very effective at fighting free radicals and preventing them from causing further skin damage. Examples of free radicals include pollution, central heating, UV rays and harsh climate. They attack proteins, fats and cell membranes as soon as they come into contact with the skin, causing signs of premature aging such as fine lines and wrinkles as well as hyperpigmentation, flaky patches of skin and loss of elasticity. Many people usually prefer to use vitamin C in their morning routine as this ingredient gives the complexion a radiant glow. You’ll also find that vitamin C can target areas of hyperpigmentation, plumping the skin and reducing the appearance of fine lines and wrinkles. The thing about vitamin C is that there are a lot of outdated studies going back to the 1950s that describe vitamin C as an unstable skin component. Thanks to improvements in modern technology, this is no longer the case as all products now contain a stable form of vitamin C. Visit The Beauty Insider to learn more about vitamin C. So please check out our blog post. Can I use salicylic acid first and then vitamin C? Yes, you absolutely can. In fact, it’s thought that using salicylic acid before using vitamin C ensures it penetrates faster and works faster. This is an efficient way to utilize two power sources, and the reason has to do with pH. For example, the skin’s natural pH is about 4.7, making it slightly acidic. Salicylic acid and vitamin C are also both acidic, and you’ll find that vitamin C is absorbed quickly into the skin. Therefore, using salicylic acid beforehand can increase the acidity of the skin and allow vitamin C to penetrate into the skin faster. While this is considered an effective way to combine two powerful ingredients, you need to be aware of your skin type and how it reacts to certain active ingredients. Even people with perfect, normal skin can experience skin sensitivity and irritation. Therefore, always consult a doctor or dermatologist before using any new products on your skin. It’s also important to follow skin application rules. In this case, you need to use the product correctly to ensure you get the best results for your skin. If you’re not sure what I mean, the basic rule for skin is to start with the thinnest consistency and work your way up to the thickest consistency. This prevents a barrier from forming on the surface, preventing other active ingredients from penetrating the skin. Can I use salicylic acid at night and vitamin C in the morning? Yes, absolutely, this is considered the most effective way to get returns without any adverse side effects. This is because there is enough time between applications to ensure that the skin’s pH levels return to balance. You’ll also find that Vitamin C is rich in antioxidants and is perfect for use in the morning to ensure your skin is protected and looking its healthiest. Due to the small size of salicylic acid molecules, it is an acid that is able to reach the deepest parts of the skin. While this is effective at keeping skin clear, it also increases the risk of irritation and photosensitivity. Therefore, many people prefer to use powerful BHAs in their evening routine without exposure to UV rays, pollution, or harsh weather. Warning: If you avoid using sunscreen every day, none of these ingredients will do what your skin needs. The combination of chemical peels and powerful ingredients increases the risk of further damage to the skin’s surface. Use SPF 50 every day to keep your skin protected and your lipid barrier healthy, even on cloudy days, keeping your skin in top condition.
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