Crepidiastrum Denticulatum Extract (Pollux CD) in Skin Care
Crepidiastrum Denticulatum Extract is a plant derived antiaging cosmeceutical ingredient that has shown to protect the skin from the effects of air pollution. It is also called Pollux CD.
It is found in antiaging wrinkle creams, especially those meant to protect skin from pollution and increase autophagy.
Plant derived natural ingredient
Crepidiastrum Denticulatum is a plant native to parts of Asia, including Korea and China. It grows in mountainous regions. The leaves and stems of the plant are used to make the extract. It is a natural ingredient that may be considered organic if grown following organic farming standards.
Diet
It has been in the diet of Koreans for many years. The young leaves are consumed as a vegetable.
Topical Use
This water soluble plant derived ingredient is found in antiaging creams.
Skin Care Products
This is one of the most exciting new antiaging ingredients in 2023 and it is so new that it is not in very many products yet. We will continue to add products here as they come out. These are the medical grade brands that have Pollux CD:
Benefits
With its unique cellular effects, Crepidiastrum Denticulatum Extract offers several benefits for skin. These benefits make it a great antiaging cream to begin in your 20s and 30s to help protect your skin.
Anti-aging: By stimulating autophagy and protecting against free radicals, it can help prevent signs of aging like wrinkles and dark spots.
Anti-inflammatory: Research showed it decreases inflammatory chemicals like interleukin-6, reducing redness and irritation.
Pollution protection: It shields skin cells from toxins found in urban pollution like cigarette smoke and heavy metals. This prevents damage from environmental factors.
Antioxidant: Its natural plant compounds scavenge free radicals, supporting the skin’s defense system.
The antioxidant and has anti-inflammatory activity are the reasons this is an exciting new antiaging skin care ingredient. It helps treat and prevent aging because it:
Increases autophagy (1,2)
Decreases cellular senescence(1)
Neutralizes free radicals (3,4)
Decreases inflammation
The unique tissue-regenerating and protective effects of Crepidiastrum Denticulatum Extract make it an intriguing ingredient for anti-aging and anti-pollution skin care products. Its plant-based compounds work at the cellular level to promote youthful, healthy skin.
It activates autophagy, the cell’s natural garbage disposal. This clears out toxins and damage that accumulate over time.
It limits inflammation by reducing inflammatory proteins like COX-2. This calms irritation.
It protects fibroblasts and keratinocytes from pollution-related chemicals like heavy metals and PAHs. This prevents toxicity from urban environments.
It acts as an antioxidant to neutralize free radicals from UV exposure and other stressors. This prevents oxidative damage.
Chemistry
The key active compounds in Crepidiastrum denticulatum extract are flavonoids and other polyphenols.
Specific flavonoids found in the extract include quercetin, kaempferol, luteolin, and apigenin. These flavonoids have antioxidant and anti-inflammatory effects in the skin.
In addition to flavonoids, the extract contains phenolic acids like chlorogenic acid and caffeic acid. It also provides sesquiterpene lactones which are anti-microbial. The combination of flavonoids, phenolic acids, and sesquiterpenes give Crepidiastrum denticulatum extract well-rounded active properties to benefit aging or at risk skin.
Safety
The EWG and CIR have not examined any safety data on this ingredient when used topially.
It has been used in studies to show it can protect the liver from alcohol damage and the kidneys from reperfusion injury. These all suggest that this ingredient is safe.
Research Studies
A recent study published in the International Journal of Molecular Sciences (2) looked at how Crepidiastrum Denticulatum Extract works on skin cells. The researchers found that it increased autophagy in fibroblasts, which are cells in the dermis. It also protected the fibroblasts from damage caused by pollution chemicals. And it decreased inflammation in keratinocytes, which are cells in the epidermis.
Autophagy:
In this study, they screened the autophagic activators from various plant extracts of family Compositae. Among them, CD extract showed increased the LC3 protein synthesis and LC3 cleavage with activating the phosphorylation of AMPK and beclin1 that are critical components in the regulation of autophagy.
Pollution protection:
It is known that pyrene and benzopyrene(BaP), which are poly-aromatic hydrocarbons(PAH), have the highest carcinogenicity and toxicity among the environmental pollutants. The treatment of CD extract recovered cell viability from BaP-induced cytotoxicity. In particular, the improvement of cell recovery was found to be superior than that of resveratrol, a typical autophagic activator.
DQH Can I use salicylic acid first and then vitamin C?
It’s easy to create a skincare routine, but knowing how to use it is another thing entirely. In most cases, if you’re not getting the desired skin results, it could be due to the layering of conflicting ingredients. So, is it possible that salicylic acid and vitamin C are such ingredients? Or are these active ingredients the duo that’s been missing from your skincare routine? If you want answers, stick around because today we are going to explain the benefits of salicylic acid and vitamin C and how they can be used in your daily life.
What are the benefits of salicylic acid for skin?
Salicylic acid is one of the most commonly used beta hydroxy acids and is favored by many people with oily, acne-prone skin. This acid is derived from willow bark, and unlike its water-soluble relatives (called alpha-hydroxy acids), salicylic acid is oil-soluble, which means it can penetrate deeper into the lower layers of the skin. Once it reaches the lower layers, it can help unclog pores of excess sebum, dirt, bacteria, debris, and impurities. This results in clearer skin tones and greater definition.
Not only does salicylic acid benefit the underlying layers, but the outer surface of the skin benefits as well. When applied to the skin, salicylic acid removes the buildup of dead skin cells. This is accomplished by breaking the bonds that hold dead cells to the surface. Over time, this can cause the complexion to look dull and prone to acne, blackheads, and other blemishes.
If you’d like to learn more about salicylic acid and how it can improve your skin, check out this dedicated blog post from a beauty insider.
What are the benefits of vitamin C for skin?
Vitamin C is considered one of the most powerful antioxidants, which means it is very effective at fighting free radicals and preventing them from causing further skin damage. Examples of free radicals include pollution, central heating, UV rays and harsh climate. They attack proteins, fats and cell membranes as soon as they come into contact with the skin, causing signs of premature aging such as fine lines and wrinkles as well as hyperpigmentation, flaky patches of skin and loss of elasticity.
Many people usually prefer to use vitamin C in their morning routine as this ingredient gives the complexion a radiant glow. You’ll also find that vitamin C can target areas of hyperpigmentation, plumping the skin and reducing the appearance of fine lines and wrinkles.
The thing about vitamin C is that there are a lot of outdated studies going back to the 1950s that describe vitamin C as an unstable skin component. Thanks to improvements in modern technology, this is no longer the case as all products now contain a stable form of vitamin C.
Visit The Beauty Insider to learn more about vitamin C. So please check out our blog post.
Can I use salicylic acid first and then vitamin C?
Yes, you absolutely can. In fact, it’s thought that using salicylic acid before using vitamin C ensures it penetrates faster and works faster.
This is an efficient way to utilize two power sources, and the reason has to do with pH. For example, the skin’s natural pH is about 4.7, making it slightly acidic. Salicylic acid and vitamin C are also both acidic, and you’ll find that vitamin C is absorbed quickly into the skin. Therefore, using salicylic acid beforehand can increase the acidity of the skin and allow vitamin C to penetrate into the skin faster.
While this is considered an effective way to combine two powerful ingredients, you need to be aware of your skin type and how it reacts to certain active ingredients. Even people with perfect, normal skin can experience skin sensitivity and irritation. Therefore, always consult a doctor or dermatologist before using any new products on your skin.
It’s also important to follow skin application rules. In this case, you need to use the product correctly to ensure you get the best results for your skin. If you’re not sure what I mean, the basic rule for skin is to start with the thinnest consistency and work your way up to the thickest consistency. This prevents a barrier from forming on the surface, preventing other active ingredients from penetrating the skin.
Can I use salicylic acid at night and vitamin C in the morning?
Yes, absolutely, this is considered the most effective way to get returns without any adverse side effects. This is because there is enough time between applications to ensure that the skin’s pH levels return to balance.
You’ll also find that Vitamin C is rich in antioxidants and is perfect for use in the morning to ensure your skin is protected and looking its healthiest. Due to the small size of salicylic acid molecules, it is an acid that is able to reach the deepest parts of the skin. While this is effective at keeping skin clear, it also increases the risk of irritation and photosensitivity. Therefore, many people prefer to use powerful BHAs in their evening routine without exposure to UV rays, pollution, or harsh weather.
Warning: If you avoid using sunscreen every day, none of these ingredients will do what your skin needs. The combination of chemical peels and powerful ingredients increases the risk of further damage to the skin’s surface. Use SPF 50 every day to keep your skin protected and your lipid barrier healthy, even on cloudy days, keeping your skin in top condition.
 in Skin Care){kind=link}