Digital Clinic for Skin & Hair Care That Works!

Menu
  • Home
  • Skin Care
  • Beauty
  • Health
Home
Beauty
“Effective Skincare: Combining Niacinamide and Matrixyl for Youthful Skin”
Beauty

“Effective Skincare: Combining Niacinamide and Matrixyl for Youthful Skin”

25 March 2025


Can You Use Niacinamide and Matrixyl at The Same Time?




Another day, another buzz ingredient making waves in the skincare industry, matrixyl is one new kid on the block we would all benefit from. Now I can hear the questions rushing around your head as I type this, don’t worry as I’ll make things a lot clearer by the end of today’s blog post. Let’s start off by explaining what matrixyl is and how it works for the skin.



What is matrixyl?




Matrixyl is the brand name of the anti-ageing peptides synthetically produced to be formulated into skincare products. You’ll find that matrixyl is a combination of Palmitoyl Tripeptide 1 and Palmitoyl Tetrapeptide 7, both these peptides act as the building blocks for the skin helping to form the structure and boost the production of collagen. This is vital for maintaining the health and appearance of the complexion. By the time we reach our mid-twenties it is understood that the levels of collagen begin to deplete by 1% each year.



The clever way matrixyl works is by stimulating the growth of elastin, collagen, and natural hyaluronic acid found in the body. Working in the skin it can reduce the appearance of fine lines and wrinkles leaving the complexion plumped, firmer, with a youthful bounce.




Another bonus to using matrixyl is the fact that anyone can use it. The only concern you may have been ensuring your skin is happy with the other ingredients it’s blended with. There is one ingredient that shouldn’t cause you too much problem, and that’s niacinamide.



What is niacinamide?




A form of vitamin B3, niacinamide delivers results for almost every skin type, including those prone to sensitivity. With its unique properties drawing moisture into the skin and locking it into place, it is also able to regulate sebum production. This makes niacinamide and highly beneficial ingredient for those prone to acne leaving the skin hydrated and nourished, something that those suffering from frequent breakouts miss out on due to overuse of harsh exfoliants and potent formulas.



If you wanted to know more about niacinamide, you can check out our dedicated blog post over on Beauty Insiders.




Now, we have had a refresher on both actives, we can move on to finding out whether you can use matrixyl and niacinamide at the same time.



What can you not mix with matrixyl?




As effective as matrixyl is for the skin, it does come with some precautions with other ingredients, such as vitamin C, also known as L-ascorbic acid, BHA, such as salicylic acid and other acids, like the popular AHA, glycolic acid.



It’s thought best to avoid using these ingredients together due to the over-exfoliation that will occur in you combine them all together. With matrixyl being considered safe enough to be used by all skin types, it is important for you to remember that matrixyl works on the skin in a similar way to retinol. By increasing the skin cell turnover, whilst the ingredient isn’t technically exfoliating the skin, if you apply an exfoliating formulation on the skin after you will overstimulate the skin, cause imbalance to the pH levels, and result in flare-ups and redness.




Can I use matrixyl and hyaluronic acid together?



You certainly can use matrixyl and hyaluronic acid together. Each active ingredient is perfectly effective to use on their own, but even more effective combined. With hyaluronic acid attracting over 1,500 times its weight in water locking it into place whilst penetrating the lower layers of the dermis. Team this with matrixyl boosting production of collagen and hyaluronic acid in the skin, your complexion is left boosted in hydration. Teaming the two together are especially effective during the winter months to counteract any excessive dryness. A bonus is the fact that both ingredients help to regulate the skin sebum levels in the skin preventing any further breakouts.




Can I use matrixyl and retinol together?



Not really, and this is only because they both benefit the skin in similar ways. If you layer matrixyl and retinol on top of each other this will lead to negative side effects, such as redness, flaking skin, itchiness, dryness, and irritation. It is important to build your skin’s tolerance by introducing retinol slowly into your daily routine.




For the best results without the side effects, I would suggest applying each ingredient on alternative days, this will help you reap the rewards of the powerhouse actives. With both matrixyl and retinol increasing the skin cell turnover, it is particularly important to ensure you apply a daily SPF to protect the face from exposure to free radicals, such as UV rays, pollution, central heating, and other environmental aggressors.



Can matrixyl be used around the eyes?




Yes, you can! You’ll find that the eye area is considerably thinner than the rest of your skin. This often leads to the eye area showing signs of ageing, such as fine lines, wrinkles, and undereye puffiness. By applying matrixyl to the under-eyes you will help boost the hydration, reducing the appearance of lines as well as improving the look of the under-eye bags that can look worse in the mornings due to fluid retention or dehydration.



Can I mix niacinamide with peptides?




Yep, it is considered perfectly safe to mix niacinamide and peptides together. Using a mixture of these two powerhouses will result in the skin’s lipid barrier maintaining the correct levels of water and oil ensuring it is strengthened and able to protect the skin surface from exposure to harmful free radical damage. There’s more to learn about mixing niacinamide and peptides together on our blog post.



There you have a little insight into how to use niacinamide and matrixyl at the same time. Even if you have already used these ingredients and have a well-established routine, it is always a good idea to consult with a doctor or dermatologist to ensure you are using the best ingredients for you and your skin’s needs. If you have any further questions you can come and find me over on the Procoal Instagram, look forward to seeing you there.
























DQH Can I use salicylic acid first and then vitamin C? It’s easy to create a skincare routine, but knowing how to use it is another thing entirely. In most cases, if you’re not getting the desired skin results, it could be due to the layering of conflicting ingredients. So, is it possible that salicylic acid and vitamin C are such ingredients? Or are these active ingredients the duo that’s been missing from your skincare routine? If you want answers, stick around because today we are going to explain the benefits of salicylic acid and vitamin C and how they can be used in your daily life. What are the benefits of salicylic acid for skin? Salicylic acid is one of the most commonly used beta hydroxy acids and is favored by many people with oily, acne-prone skin. This acid is derived from willow bark, and unlike its water-soluble relatives (called alpha-hydroxy acids), salicylic acid is oil-soluble, which means it can penetrate deeper into the lower layers of the skin. Once it reaches the lower layers, it can help unclog pores of excess sebum, dirt, bacteria, debris, and impurities. This results in clearer skin tones and greater definition. Not only does salicylic acid benefit the underlying layers, but the outer surface of the skin benefits as well. When applied to the skin, salicylic acid removes the buildup of dead skin cells. This is accomplished by breaking the bonds that hold dead cells to the surface. Over time, this can cause the complexion to look dull and prone to acne, blackheads, and other blemishes. If you’d like to learn more about salicylic acid and how it can improve your skin, check out this dedicated blog post from a beauty insider. What are the benefits of vitamin C for skin? Vitamin C is considered one of the most powerful antioxidants, which means it is very effective at fighting free radicals and preventing them from causing further skin damage. Examples of free radicals include pollution, central heating, UV rays and harsh climate. They attack proteins, fats and cell membranes as soon as they come into contact with the skin, causing signs of premature aging such as fine lines and wrinkles as well as hyperpigmentation, flaky patches of skin and loss of elasticity. Many people usually prefer to use vitamin C in their morning routine as this ingredient gives the complexion a radiant glow. You’ll also find that vitamin C can target areas of hyperpigmentation, plumping the skin and reducing the appearance of fine lines and wrinkles. The thing about vitamin C is that there are a lot of outdated studies going back to the 1950s that describe vitamin C as an unstable skin component. Thanks to improvements in modern technology, this is no longer the case as all products now contain a stable form of vitamin C. Visit The Beauty Insider to learn more about vitamin C. So please check out our blog post. Can I use salicylic acid first and then vitamin C? Yes, you absolutely can. In fact, it’s thought that using salicylic acid before using vitamin C ensures it penetrates faster and works faster. This is an efficient way to utilize two power sources, and the reason has to do with pH. For example, the skin’s natural pH is about 4.7, making it slightly acidic. Salicylic acid and vitamin C are also both acidic, and you’ll find that vitamin C is absorbed quickly into the skin. Therefore, using salicylic acid beforehand can increase the acidity of the skin and allow vitamin C to penetrate into the skin faster. While this is considered an effective way to combine two powerful ingredients, you need to be aware of your skin type and how it reacts to certain active ingredients. Even people with perfect, normal skin can experience skin sensitivity and irritation. Therefore, always consult a doctor or dermatologist before using any new products on your skin. It’s also important to follow skin application rules. In this case, you need to use the product correctly to ensure you get the best results for your skin. If you’re not sure what I mean, the basic rule for skin is to start with the thinnest consistency and work your way up to the thickest consistency. This prevents a barrier from forming on the surface, preventing other active ingredients from penetrating the skin. Can I use salicylic acid at night and vitamin C in the morning? Yes, absolutely, this is considered the most effective way to get returns without any adverse side effects. This is because there is enough time between applications to ensure that the skin’s pH levels return to balance. You’ll also find that Vitamin C is rich in antioxidants and is perfect for use in the morning to ensure your skin is protected and looking its healthiest. Due to the small size of salicylic acid molecules, it is an acid that is able to reach the deepest parts of the skin. While this is effective at keeping skin clear, it also increases the risk of irritation and photosensitivity. Therefore, many people prefer to use powerful BHAs in their evening routine without exposure to UV rays, pollution, or harsh weather. Warning: If you avoid using sunscreen every day, none of these ingredients will do what your skin needs. The combination of chemical peels and powerful ingredients increases the risk of further damage to the skin’s surface. Use SPF 50 every day to keep your skin protected and your lipid barrier healthy, even on cloudy days, keeping your skin in top condition.
Share
Tweet
Email
Prev Article
Next Article

Related Articles

Salmon Sperm DNA: Polydeoxyribonucleotide (PDRN) in Skincare

Salmon Sperm DNA: Polydeoxyribonucleotide (PDRN) in Skincare

Effective Ways to Reduce Deep Wrinkles Around the Mouth

Effective Ways to Reduce Deep Wrinkles Around the Mouth

Recent Posts

  • Cleansing Oil: A Gentle Skincare Essential for All Types
    Cleansing Oil: A Gentle Skincare Essential for …
    3 June 2025 0
  • Skin Cycling Explained: A Smarter Skincare Routine
    Skin Cycling Explained: A Smarter Skincare Routine
    3 June 2025 0
  • Best Skincare Ingredients to Combat Acne and Breakouts
    Best Skincare Ingredients to Combat Acne and …
    3 June 2025 0
  • Skin Benefits and Risks of Drinking Lemon Water Daily
    Skin Benefits and Risks of Drinking Lemon …
    3 June 2025 0
  • How Your Skin Changes After You Stop Retinol Use
    How Your Skin Changes After You Stop …
    3 June 2025 0

Popular Posts

  • Gluconolactone: The Sensitive Skin Hero You Haven’t Tried Yet
    Gluconolactone: The Sensitive Skin Hero You Haven’t …
    1 June 2025 0
  • Retinoic Acid Receptors: Key Drivers of Effective Skincare Treatments
    Retinoic Acid Receptors: Key Drivers of Effective …
    5 May 2025 0
  • Understanding Retinoid Science: How Retinol Transforms Skin Health
    Understanding Retinoid Science: How Retinol Transforms Skin …
    5 May 2025 0
  • Best Retinol Alternatives for Sensitive Skin, Pregnancy, and Acne
    Best Retinol Alternatives for Sensitive Skin, Pregnancy, …
    5 May 2025 0
  • Is Retinol Safe During Pregnancy? Risks, Guidelines, and Alternatives
    Is Retinol Safe During Pregnancy? Risks, Guidelines, …
    5 May 2025 0

Digital Clinic for Skin & Hair Care That Works!

Copyright © 2025 Digital Clinic for Skin & Hair Care That Works!
Theme by MyThemeShop.com

Ad Blocker Detected

Our website is made possible by displaying online advertisements to our visitors. Please consider supporting us by disabling your ad blocker.

Refresh