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Hexylresorcinol in Skincare
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Hexylresorcinol in Skincare

17 February 2025


Hexylresorcinol in Skincare




Hexylresorcinol is considered one of the most effective skin lightening compounds in use in skin care today, and is commonly found in products used to lighten dark spots on the skin.



Hexylresorcinol is better for sensitive skin than the similar compound resorcinol.




It also has antibacterial activity.



Hexylresorcinol is completely safe to use unless you are pregnant or allergic to it.




To find out if this ingredient is the best for your skin type, shop using your Baumann Skin Type.



Is hexylresorcinol safe for skin?




Hexylresorcinol is safe for use in skin care products.



It is considered a clean ingredient and has a score of 1 from the EWG (environmental working group).




It so safe that it is used in the production of some foods like certain fruits and grains to lighten colors or correct blemishes on food.



Does hexylresorcinol have any side effects?




This skin care ingredient and food additive is not dangerous unless you have an allergy to it.



An allergy to this ingredient can cause a slight rash, redness, or irritation on the applied area.




If you are worried that you might be allergic to hexylresorcinol, apply a small amount of product to a small patch of skin; look for redness or irritation within about 12-24 hours.



If redness or a rash occurs, do not use the product.




Another possible side effect of this skin lightening ingredient is a halo around treated dark spots.



To avoid this, do not apply the product outside of target dark spots.




Hexylresorcinol products may cause irritation on applied areas if used in too great a quantity or frequency.

Overuse and irritation may cause “Post Inflammatory Pigmentary Alteration” (PIPA), a darkening of the skin.

To avoid irritation, always combine with the correct products in a skin care routine customized for your Baumann Skin Type.

is hexylresorcinol safe while pregnant

Can I use hexylresorcinol when I am pregnant?

Pregnant women are advised not to use products with hexylresorcinol because resorcinol based compounds can enter the bloodstream and have been found in urine.

There are other ways to treat conditions like melasma during pregnancy without resorcinol or hexylresorcinol-based products.

To find the right products for you, shop by your Baumann Skin Type.

Take the Quiz

Benefits

Skin benefits of hexylresorcinol include:

Treating Hyperpigmentation

Anti-aging

Treats acne by decreasing acne causing bacteria

Lightening skin

Antioxidant

Anti-inflammatory

Anti-Glycation

results from hexylresorcinol

How long does it take to see results

If you are using this ingredient in the proper skin care routine for your skin type, you can expect results in 8-16 weeks.

If you have used hexylresorcinol for over 3 months and have not seen results, click here.

What is hexylresorcinol good for?

Some of the notable benefits of this ingredient include:

Lightening dark spots

Alleviating acne

Treating sun damage

Improving aged skin

Skin lightening

Hexylresorcinol is a Tyrosinase Inhibitor

It prevents the production of the skin pigment melanin.

Apply it directly to dark spots 1-2 times a day as part of a complete skin lightening regimen.

Take the Quiz

choose a skin lightening serum based on your skin type

What are the best products with hexylresorcinol?

6 best dermatologist-recommended hexylresorcinol products are:

Medature Hydro Bright Treatment- one of the most affordable options

Murad Multivitamin Infusion Oil – best for very dry skin

Derma Made Mela Fade- Also has tranexamic acid and kojic acid.

Replenix Pigment Correcting Brightening Cream- Is a cream so it is more moisturizing. It also has arbutin. Not as strong as other options, but the cheapest option.

PCA Pigment Gel Pro- Often too irritating for sensitive skin types.

MDSolarSciences MD Revitalize Retinol Serum- Combines calming agents like caffeine with retinol.

retinol

Can you use Hexylresorcinol with retinol?

Retinol and hexylresorcinol may be used together in skin care routines to treat hyperpigmentation.

Usually hexylresorcinol is used in step 3 in the am and pm routine, while retinol is used in step 5 of the pm routine, but this varies by Baumann Skin Type.

Retinol is a type of retinoid. Retinol helps with desquamation and tyrosinase inhibition, speeding the results of hexylresorcinol.

MDSolarSciences MD Revitalize Retinol Serum combines retinol and hexylresorcinol together in one serum.

hydroquinone

Is it like Hydroquinone?

Both compounds are used to treat hyperpigmentation, however they are very different.

Hexylresorcinol products are free of the safety concerns commonly associated with hydroquinone products.

Hexylresorcinol permeates the skin’s cellular membranes more efficiently than hydroquinone, kojic Acid, or licorice extract.

Hexylresorcinol products are considered cosmetics and are available over the counter or online.

Hydroquinone products are considered drugs only available by prescription in the United States.

resorcinol vs hexylresorcinol

What are the differences between Hexylresorcinol and Resorcinol?

Hexylresorcinol (HR) shares many qualities with resorcinol, but has some notable differences.

HR passes through the skin’s cell membranes more efficiently than resorcinol.

HR diffuses better in liquids like the liquid inside our skin cells.

HR is less irritating to sensitive skin types than resorcinol.

Resorcinol has a EWG rating of 7 due to risk of skin allergy.

niacinamide

What are the differences between Hexylresorcinol and Niacinamide?

The main difference between the two compounds is that Niacinamide is a PAR-2 Blocker,

PAR-2 blockers do not prevent the production of melanin, they block the transfer of melanin filler melanocytes into keratinocyte skin cells.

Hexylresorcinol is a tyrosinase Inhibitor which prevent the formation of pigment.

Niacinamide is anti-inflammatory and helps increase cellular energy.

Both offer anti-aging and skin lightening benefits but via different pathways.

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Can you use Hexylresorcinol and Niacinamide together?

Niacinamide and hexylresorcinol can be mixed and used together.

The two ingredients compliment each other because they block different pathways in the skin pigmentation process.

Niacinamide is more gentle than hexylresorcinol for most skin types unless you have an allergy to it.

How many times a day should I use Hexylresorcinol?

Most skin care regimen use this ingredient two times per day, in the morning and night, however it depends upon your Baumann Skin Type.

Refer to Your Baumann Skin Type Regimen for instructions on frequency of use.

Products

There are a variety of products on the Skin Care market which include other similar Tyrosinase Inhibitors.

Here are some products from our website related to or containing Hexylresorcinol.

To get an exact skin care routine, shop by your skin type.

DQH Knowledge drop: In your 20s, your skin cell turnover decreases. (Cell turnover is a key component in keeping your skin youthful.) You know what else slows down? Your collagen production. Starting in your 20s, collagen decreases by about 1 percent per year. Should you want to prevent fine lines and wrinkles, start by eliminating behaviors that contribute to premature aging. “If it’s bad for you, it’s bad for your skin,” says dermatologist Michel Somenek. “Cigarette smoking reduces blood flow to the skin and causes premature wrinkling and a dull skin texture. Making the repeated pursed motion to inhale can also cause smoker’s lines. Alcohol and recreational drugs are toxins for the skin that damage its cellular structure and DNA,” Somenek tells us. “The faster you eliminate vices while you are young, the better chance your skin and body have to recuperate.” Also, adopting an anti-aging routine in your 20s is key. After all, the best offense is a good defense. We spoke to Somenek and experts Joshua Ross and Audrey Kunin to find out more. Keep reading for the best anti-aging products for your 20s, according to skincare professionals. Sunscreen “We all know that the sun is the number one cause of skin aging and starting the prevention in your 20s is very important,” Ross says. “The majority of your sun damage won’t start to appear until you’re in your 30s, so don’t wait until you see it surface or you’ll be behind the curve. Stay ahead of it with a good-quality zinc-based sunscreen worn daily.” Farmacy Green Defense Daily Mineral Sunscreen An invisible sunscreen with SPF 30, plus botanical extracts meant to protect skin with tons of antioxidants. Bonus: It’s clean and fine to use under makeup. Bareminerals Complexion Rescue™ Tinted Moisturizer Broad Spectrum SPF 30 Although we recommend you use your SPF and moisturizer separately, we also understand moments when you don’t have time or energy for that extra step. For those times, this bareMinerals moisturizer is a great thing to have on hand. Vitamin C Serum “A great introduction to anti-aging is to start with a vitamin C serum in your morning skincare routine,” Ross says. “It’s a powerful antioxidant that will neutralize free radicals and brighten the skin.” He adds that it’s a great way to counteract the effects of the sun’s harmful rays, which, as previously mentioned, are among the biggest causes of premature aging. Drunk Elephant C-Firma™ Vitamin C Day Serum The Drunk Elephant C-Firma is a lightweight serum that promises to give skin a glow by combining the brightening powers of vitamin C with ferulic acid, l-ascorbic acid, and vitamin E. The included sodium hyaluronate is meant to replace hydration loss, so you shouldn’t have to deal with any irritation. Sunday Riley C.E.O. Rapid Flash Brightening Serum This potent serum is jam-packed with vitamin C (15 percent, to be exact), which means it’s a potential superstar at both brightening skin and dousing it in antioxidants. Peptides Using peptides on your skin has many benefits, says Somenek. “The skin barrier is what defends the body against pollution, UV rays, bacteria, and toxins. It can be damaged by several everyday factors. Using topical peptides aids in building a stronger barrier,” he says. “Peptides comprise elastic fibers, which are a type of protein. These fibers help to make skin appear taut and firm. Peptides can also help repair damaged skin, relieve inflammation, and even out skin tone. Some peptides can kill acne-causing bacteria that is common in 20-somethings.” Kunin agrees, saying, “Peptides are an excellent entry point for supporting collagen.” She recommends looking for face and eye treatments that contain these collagen-boosting powerhouses. Charlotte Tilbury Magic Eye Rescue Cream This Charlotte Tilbury super-emollient eye cream has a base of coconut oil and shea butter (read: it’s incredibly hydrating). Botanicals plus peptides are meant to help reduce dark circles and boost collagen, respectively. This creamy moisturizer serves up potent collagen-boosting peptides and pycnogenol, and antioxidant-rich vitamin C. “Instead of sitting on top of the skin, peptides penetrate the outer layer so they go deep. The ‘signals’ they send tell the cells to produce elastin and collagen, which are needed for youthful-looking skin,” explains Somenek. At-Home Peel Pads Remember that skin cell turnover fiasco we talked about earlier? One way to help support it is by exfoliating. “Exfoliation is important to help keep skin fresh and luminous,” Kunin says. She recommends using at-home peel pads as an easy and effective way to exfoliate. “The goal in your 20s is to fight the slowing pace of cell turnover. It is wise to use products that gently exfoliate, yet still remove oil and other impurities. Products that have Alpha Hydroxy Acids (AHA) or Beta Hydroxy Acids (BHA) are a good choice.” According to Somenek, you should only exfoliate two to three times a week. “People of all ages are guilty of over-exfoliating and that can be too much of a good thing,” he says. Dermadoctor Kakadu C Intensive Vitamin C Peel Pad A few swipes of this Derma Doctor powerful peel pad promise to leave your skin glowing and smooth, thanks to the seven (yes, seven) types of chemical exfoliants, including AHA and BHA. It also contains vitamin C via Kakadu plum extract for added brightening and antioxidant protection. KEY INGREDIENTS Kakadu plum extract is sourced from the Kakadu plum, a fruit grown in northern Australia. It contains vitamin C, which restores the skin’s natural barrier, increases collagen production, and soothes irritation. Dr. Dennis Gross Skincare Alpha Beta® Universal Daily Peel Pads These are the gold standard of peel pads, with a cult following and over 900 five-star reviews on Sephora. They’re easy to use and contain a blend of anti-aging exfoliating acids. Emollient Night Cream “In your 20s, you need to start upping the hydration in your skincare routine. You may have been cautious of over-moisturizing because of acne in your teens, but as you enter your 20s, your skin transitions and becomes drier,” Ross says. “I recommend an emollient night cream added into your evening skincare regimen.” “Twenty-somethings need to make sure that they are not using creams that will clog their pores and cause excess oil production,” says Somenek. Opt for non-comedogenic products. Cerave Skin Renewing Night Cream One great choice is the CeraVe Skin Renewing Night Cream, which is a non-comedogenic night cream that leaves skin soft and glowy. It combines the moisturizing powers of ceramides and hyaluronic acid. RoC Retinol Correxion Max Hydration Creme “The best night cream ingredients contain retinol, benzoyl peroxide, and/or salicylic acid or hyaluronic acid. The goal is to moisturize, yet remove excess oil,” says Somenek. This Roc Retinol Correxion cream fits the bill as it contains both hyaluronic acid and retinol so it promises to moisturize while also being non-comedogenic.
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