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How Long Does Retinol Take To Get Rid Of Wrinkles?
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How Long Does Retinol Take To Get Rid Of Wrinkles?

28 February 2025


How Long Does Retinol Take To Get Rid Of Wrinkles?




How long do retinoids take to improve wrinkles? Retinoids can take months to see improvement of wrinkles, but how fast you see results of the benefits of retinol depends upon what strength of retinoid you use. Retinol takes the longest to work on wrinkles but it is the only retinoid that works well that you can get without a prescription. To get rid of wrinkles, you need to combine retinol or other retinoids in a complete antiaging skin care routine. You can combine retinoids with other antiaging ingredients to make them work faster.



Shop by your Baumann Skin Type to find the best retinoid for your skin type.




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Before we discuss how long it takes to see results from retinol, let’s discuss nomenclature.




Retinol is a type of retinoid.1 There are prescription and cosmetic retinoids:



Retinol is fa cosmetic retinoid found in cosmetic products




Adapalene is in cosmetic products, over-the-counter products for acne, and prescription products



Tretinoin is prescription ad is FDA approved for aging and acne




Tazarotene is prescription only and is FDA approved for aging and acne



Trifarotene in prescription products for acne.




The only retinoids FDA approved to treat wrinkles are tretinoin and tazarotene. However, studies have shown that retinol is effective on wrinkles.2



This blog will review the peer-reviewed evidence-based data on using retinol and retinoids for wrinkles.




How does retinol work to get rid of wrinkles?



How Soon Can Changes In Skin From Retinoids Be Seen With A Microscope?




In a study3 comparing tretinoin 0.1% and retinol 0.1%, both retinoids showed skin improvement under the microscope at 4 weeks. However, it usually takes at least 12- 24 weeks to see skin changes without a microscope.



How Fast Can Retinol Improve Wrinkles?




Studies have shown that retinol improves wrinkles. Retinol 0.1% was shown to improve crow’s feet lines by 44% at 52 weeks (one year).4 How fast wrinkles improve depends on the potency, frequency and amount of retinoid used. The other antiaging ingredients and products in your skin care routine will also affect how fast retinol works.



You do not want to start a strong retinoid too quickly because it can lead to retinoid side effects. Remember that prescription retinoids are stronger than retinol so you will see results faster with prescription retinoids. However, we advise you to first begin a low-strength retinol and work your way up slowly to a stronger retinol and then convert over to a prescription strength retinoid. Click here to see how to use retinoids.




Or even better- shop by your skin type and we will tell you exactly which retinol brands to choose from.



Take the Quiz




Which Retinoid Cream Improves Wrinkles The Fastest?



In 2001, a study (5) compared these prescription retinoids:




Tazarotene 0.01%



Tazarotene0.025%




Tazarotene 0.05%



Tazarotene 0.1%




Tretinoin 0.05% cream



These prescription retinoids were applied every night for 24 weeks.


All of the percentages of tazarotene and the 0.05% tretinoin improved fine wrinkles and evened skin tone.

Tazarotene 0.1% worked the best at 8, 12, and 20 weeks but had a higher rate of side effects.

However, by 24 weeks, tretinoin 0.05% and tazarotene 0.1% had similar results.

This study shows that wrinkles improve the fastest with tazarotene 0.1% as compared to tretinoin 0.05% and lower doses of tazarotene.

Studies showing how fast prescription retinoids get rid of wrinkles:

How Fast Does Tretinoin Improve Wrinkles?

Most people who use tretinoin see improvement of wrinkles by 24 weeks.6 A higher percent of tretinoin (0.1%) has faster improvement of wrinkles as compared to a tretinoin strength of 0.05%.

Higher-strength tretinoin improves wrinkles faster than low doses do, however, with time, they both improve wrinkles the same.

A 1995 study compared wrinkle improvement placebo cream vs tretinoin 0.025% cream vs tretinoin 0.1%.7 As expected, the 0.025% cream was associated with fewer side effects than the 0.1% tretinoin. At 48 weeks, the improvement of wrinkles was the same (there was no statistical difference) for both doses of tretinoin- showing that lower strength retinoids will have the same improvement as the higher strength ones with time.

Do Stronger Retinoids Improve Wrinkles Faster?

Higher percentages of retinoids improve wrinkles faster, so if you want to get rid of wrinkles quickly, a stronger retinoid is the way to go but be prepared to have more side effects. Many studies have shown that weaker retinoids take longer to see results, but have fewer side effects.8

One study of tretinoin emollient cream for 48 weeks compared two groups: the first group used tretinoin 0.05% and the other group used tretinoin 0.01%. At 24 weeks, more improvement was seen in the 0.05% group as expected because this was a more potent form of retinoid. The 0.01% group showed less improvement at 24 weeks but continued to improve from weeks 24- 48. By 48 weeks, the lower dose group still did not achieve the levels of improvement observed with the stronger 0.05% formulation. These results demonstrate that higher doses yield a faster and better response at 48 weeks, but lower doses do cause improvement in wrinkles and skin appearance.

How Fast Does Tazarotene Improve Wrinkles?

Studies have shown that tazarotene 0.1% is the most effective antiaging retinoid. It was approved by the FDA in 19979 to improve the appearance of fine facial wrinkles and uneven skin tone. Results may be seen as early as 8 weeks.10 One study of tazarotene 0.1% gel ( compared to placebo) used on the arms showed improvement of wrinkles and skin texture at 12 weeks.11 A summary of research trials using tazarotene for wrinkles can be found in this reference.12

In summary- the higher a retinoid percentage is- the faster wrinkles and fine lines will go away but more side effects will be seen. Retinoid side effects can lead to inflammation and pigmentation. Inflammation is a cause of skin aging and an uneven skin tone is undesirable. For this reason- we recommend starting with a low strength retinoid and slowly working your way up to the strongest retinoid that you can tolerate without getting skin inflammation.

The best way to find the retinoid that will work fastest for you and learn what products to combine it with in your skin care routine to speed results is to shop by your Baumann Skin Type.

DQH Can I use salicylic acid first and then vitamin C? It’s easy to create a skincare routine, but knowing how to use it is another thing entirely. In most cases, if you’re not getting the desired skin results, it could be due to the layering of conflicting ingredients. So, is it possible that salicylic acid and vitamin C are such ingredients? Or are these active ingredients the duo that’s been missing from your skincare routine? If you want answers, stick around because today we are going to explain the benefits of salicylic acid and vitamin C and how they can be used in your daily life. What are the benefits of salicylic acid for skin? Salicylic acid is one of the most commonly used beta hydroxy acids and is favored by many people with oily, acne-prone skin. This acid is derived from willow bark, and unlike its water-soluble relatives (called alpha-hydroxy acids), salicylic acid is oil-soluble, which means it can penetrate deeper into the lower layers of the skin. Once it reaches the lower layers, it can help unclog pores of excess sebum, dirt, bacteria, debris, and impurities. This results in clearer skin tones and greater definition. Not only does salicylic acid benefit the underlying layers, but the outer surface of the skin benefits as well. When applied to the skin, salicylic acid removes the buildup of dead skin cells. This is accomplished by breaking the bonds that hold dead cells to the surface. Over time, this can cause the complexion to look dull and prone to acne, blackheads, and other blemishes. If you’d like to learn more about salicylic acid and how it can improve your skin, check out this dedicated blog post from a beauty insider. What are the benefits of vitamin C for skin? Vitamin C is considered one of the most powerful antioxidants, which means it is very effective at fighting free radicals and preventing them from causing further skin damage. Examples of free radicals include pollution, central heating, UV rays and harsh climate. They attack proteins, fats and cell membranes as soon as they come into contact with the skin, causing signs of premature aging such as fine lines and wrinkles as well as hyperpigmentation, flaky patches of skin and loss of elasticity. Many people usually prefer to use vitamin C in their morning routine as this ingredient gives the complexion a radiant glow. You’ll also find that vitamin C can target areas of hyperpigmentation, plumping the skin and reducing the appearance of fine lines and wrinkles. The thing about vitamin C is that there are a lot of outdated studies going back to the 1950s that describe vitamin C as an unstable skin component. Thanks to improvements in modern technology, this is no longer the case as all products now contain a stable form of vitamin C. Visit The Beauty Insider to learn more about vitamin C. So please check out our blog post. Can I use salicylic acid first and then vitamin C? Yes, you absolutely can. In fact, it’s thought that using salicylic acid before using vitamin C ensures it penetrates faster and works faster. This is an efficient way to utilize two power sources, and the reason has to do with pH. For example, the skin’s natural pH is about 4.7, making it slightly acidic. Salicylic acid and vitamin C are also both acidic, and you’ll find that vitamin C is absorbed quickly into the skin. Therefore, using salicylic acid beforehand can increase the acidity of the skin and allow vitamin C to penetrate into the skin faster. While this is considered an effective way to combine two powerful ingredients, you need to be aware of your skin type and how it reacts to certain active ingredients. Even people with perfect, normal skin can experience skin sensitivity and irritation. Therefore, always consult a doctor or dermatologist before using any new products on your skin. It’s also important to follow skin application rules. In this case, you need to use the product correctly to ensure you get the best results for your skin. If you’re not sure what I mean, the basic rule for skin is to start with the thinnest consistency and work your way up to the thickest consistency. This prevents a barrier from forming on the surface, preventing other active ingredients from penetrating the skin. Can I use salicylic acid at night and vitamin C in the morning? Yes, absolutely, this is considered the most effective way to get returns without any adverse side effects. This is because there is enough time between applications to ensure that the skin’s pH levels return to balance. You’ll also find that Vitamin C is rich in antioxidants and is perfect for use in the morning to ensure your skin is protected and looking its healthiest. Due to the small size of salicylic acid molecules, it is an acid that is able to reach the deepest parts of the skin. While this is effective at keeping skin clear, it also increases the risk of irritation and photosensitivity. Therefore, many people prefer to use powerful BHAs in their evening routine without exposure to UV rays, pollution, or harsh weather. Warning: If you avoid using sunscreen every day, none of these ingredients will do what your skin needs. The combination of chemical peels and powerful ingredients increases the risk of further damage to the skin’s surface. Use SPF 50 every day to keep your skin protected and your lipid barrier healthy, even on cloudy days, keeping your skin in top condition.
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