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Layering Niacinamide and Azelaic Acid: A Simple Routine
Beauty

Layering Niacinamide and Azelaic Acid: A Simple Routine

23 April 2025


How To Use Niacinamide and Azelaic Acid




With the beauty industry being such a busy hive of must try formulas and hero ingredients reigning supreme, you’ll find there are a few ingredients that enjoy staying under the radar. But today, we are going to shine some light on Azelaic acid and niacinamide and how they can be used together in your daily skincare routine. Hopefully, once we bring both these skin heroes to your attention, you’ll wonder how you ever had a routine without them!



Now, if you’re reading this and thinking to yourself, what on earth is azelaic acid and niacinamide? This next part is for you!




What does Niacinamide do for the skin?



Niacinamide is a form of vitamin B3 and can benefit all skin types due to the fact it has humectant properties. This means niacinamide can draw in moisture into the skin and lock it into place, resulting in the protective skin barrier remains fully functioning. With the skin barrier containing the correct levels of water and oil it can prevent any further damage to the skin caused by exposure to free radical such as pollution, UV rays and other environmental aggressors. Niacinamide also carries the benefits of being able to regulate the sebum production in the skin meaning it can help to rebalance and promote clarity for the complexion.




What does Azelaic Acid do for the skin?



Obtained from various grains, such as barley, wheat and rye and is often formulated in products to work as a leave on exfoliant. It is usually mistaken as being a member of the AHA family, azelaic acid delivers cell communicating skills by “telling” the skin cells on the surface how to behave and over time work at having a smoother, vibrant complexion. It can combat signs of pigmentation and reduce any visible fine lines and wrinkles; it can also help soothe any flare-ups of rosacea. As effective as azelaic acid is at perfecting the skin it can increase photosensitivity so always ensure you a daily SPF of 30 and above.




Can you use niacinamide and azelaic acid together?



You can indeed, what you may find is that niacinamide and azelaic acid form a powerful skin perfecting duo. Whilst azelaic acid is ridding the surface build-up of dead skin cells, bacteria, and impurities whilst niacinamide works at aiding a boost in hydration and restoring the skin barrier to its healthiest state.




When it comes to formulations, you’ll find that niacinamide and azelaic acid are found in products such as serums, face oils and moisturisers. This is an important point to remember as generally these products remain to on the skin for a longer amount of time. This usually results in the potency of each ingredient being a higher percentage meaning you can often see results quicker. With this, it does mean there is a higher risk of irritation and other skin reactions so ensuring you have performed a patch test on the skin beforehand is vital to avoid any of this.



If you wanted to find out more about using niacinamide and azelaic acid together, check out our dedicated blog post.




Do you use niacinamide before azelaic acid?



This first depends on the product each ingredient is formulated in, as I have mentioned in previous posts applying skincare products from thinnest to thickest allows each product to absorb into the skin. If I was to give you my own personal thoughts, I would suggest using a serum enriched in azelaic acid first, followed by a moisturiser packed with niacinamide.




By using the azelaic acid formula first, you are removing the barrier on the surface of the skin created by a build-up of dead skin cells, revealing new skin underneath. Once you have applied niacinamide you’ll maintain the overall health and glowing appearance of your skin with the peace of mind there won’t be any signs of irritation.



What do you not mix with niacinamide?




With its antioxidant and anti-inflammatory properties there are a great deal of skin ingredients to team with niacinamide. With its humectant traits it is helps keep the skin hydrated, soothed and balanced making it an ideal teammate for any other ingredients that are more potent, such as AHA like glycolic acid or BHA such as salicylic acid.



As for skin ingredients that should not be mixed with niacinamide, it is considered that vitamin C delivers similar results and when used together can result in both ingredients counteracting each other rendering them both useless for the skin. Having said that there is nothing stopping you from applying a serum enriched in vitamin C during your morning routine, and niacinamide serum in the evening to reap the rewards with none of the side effects.




Does azelaic acid make you purge?



Yes, it certainly does, but that isn’t necessarily a bad thing. Azelaic acid can speed up the skin cell turn over causing a sudden flare-up in breakouts on the face. This is simply a sign that the azelaic acid is doing its job and ridding the skin of excess sebum, dead skin cells, impurities, and bacteria that in the long run can cause a larger number of problems. Be mindful that if these breakouts are accompanied with discomfort, itching, rashes, or flakiness, this is a sign that azelaic acid is too harsh for your skin and should stop using it instantly. Remember that if you have any concerns with introducing azelaic acid into your routine its best to consult with a doctor or dermatologist to ensure it’s the best ingredient for you and your skin.




Does azelaic acid help with acne scars?



Thanks to azelaic acid helping with skin renewal you’ll find it is able to reduce the appearance of hyperpigmentation and fade dark spots that are often a result of post acne scarring. By sloughing away dead skin cells you’ll find dark spots become lighter over time resulting in them becoming less noticeable to the naked eye. To prevent further sun damage and the overproduction of melanin it is best to remember to apply a daily SPF of 30 and above to prevent further damage from developing.




Should I moisturise before or after azelaic acid?



Taking into consideration the fact that moisturisers have a thick consistency, it is best to apply them at the final stages of your routine. Another benefit of moisturisers is the fact they contain high levels of water and once applied to the skin can help keep the skin surface hydrated and plumped. They are also able to form a protective barrier on the outer layer ensuring any potent ingredients or serums you applied beforehand can work their magic whilst undisturbed from exposure to free radical factors such as UV sun rays, pollution and other environmental aggressors.




So, whether you use niacinamide and azelaic acid separately or teamed together you’ll find they create an overall soothing, hydrating and reviving skin power duo. As always, I would suggest if you were new to these ingredients always check with a doctor or medical professional.



If you have any questions, or just love all things skincare, come, and join us over on Instagram, and don’t forget to check out our latest episode of The Green Sofa over on our YouTube channel.



















































DQH Can I use salicylic acid first and then vitamin C? It’s easy to create a skincare routine, but knowing how to use it is another thing entirely. In most cases, if you’re not getting the desired skin results, it could be due to the layering of conflicting ingredients. So, is it possible that salicylic acid and vitamin C are such ingredients? Or are these active ingredients the duo that’s been missing from your skincare routine? If you want answers, stick around because today we are going to explain the benefits of salicylic acid and vitamin C and how they can be used in your daily life. What are the benefits of salicylic acid for skin? Salicylic acid is one of the most commonly used beta hydroxy acids and is favored by many people with oily, acne-prone skin. This acid is derived from willow bark, and unlike its water-soluble relatives (called alpha-hydroxy acids), salicylic acid is oil-soluble, which means it can penetrate deeper into the lower layers of the skin. Once it reaches the lower layers, it can help unclog pores of excess sebum, dirt, bacteria, debris, and impurities. This results in clearer skin tones and greater definition. Not only does salicylic acid benefit the underlying layers, but the outer surface of the skin benefits as well. When applied to the skin, salicylic acid removes the buildup of dead skin cells. This is accomplished by breaking the bonds that hold dead cells to the surface. Over time, this can cause the complexion to look dull and prone to acne, blackheads, and other blemishes. If you’d like to learn more about salicylic acid and how it can improve your skin, check out this dedicated blog post from a beauty insider. What are the benefits of vitamin C for skin? Vitamin C is considered one of the most powerful antioxidants, which means it is very effective at fighting free radicals and preventing them from causing further skin damage. Examples of free radicals include pollution, central heating, UV rays and harsh climate. They attack proteins, fats and cell membranes as soon as they come into contact with the skin, causing signs of premature aging such as fine lines and wrinkles as well as hyperpigmentation, flaky patches of skin and loss of elasticity. Many people usually prefer to use vitamin C in their morning routine as this ingredient gives the complexion a radiant glow. You’ll also find that vitamin C can target areas of hyperpigmentation, plumping the skin and reducing the appearance of fine lines and wrinkles. The thing about vitamin C is that there are a lot of outdated studies going back to the 1950s that describe vitamin C as an unstable skin component. Thanks to improvements in modern technology, this is no longer the case as all products now contain a stable form of vitamin C. Visit The Beauty Insider to learn more about vitamin C. So please check out our blog post. Can I use salicylic acid first and then vitamin C? Yes, you absolutely can. In fact, it’s thought that using salicylic acid before using vitamin C ensures it penetrates faster and works faster. This is an efficient way to utilize two power sources, and the reason has to do with pH. For example, the skin’s natural pH is about 4.7, making it slightly acidic. Salicylic acid and vitamin C are also both acidic, and you’ll find that vitamin C is absorbed quickly into the skin. Therefore, using salicylic acid beforehand can increase the acidity of the skin and allow vitamin C to penetrate into the skin faster. While this is considered an effective way to combine two powerful ingredients, you need to be aware of your skin type and how it reacts to certain active ingredients. Even people with perfect, normal skin can experience skin sensitivity and irritation. Therefore, always consult a doctor or dermatologist before using any new products on your skin. It’s also important to follow skin application rules. In this case, you need to use the product correctly to ensure you get the best results for your skin. If you’re not sure what I mean, the basic rule for skin is to start with the thinnest consistency and work your way up to the thickest consistency. This prevents a barrier from forming on the surface, preventing other active ingredients from penetrating the skin. Can I use salicylic acid at night and vitamin C in the morning? Yes, absolutely, this is considered the most effective way to get returns without any adverse side effects. This is because there is enough time between applications to ensure that the skin’s pH levels return to balance. You’ll also find that Vitamin C is rich in antioxidants and is perfect for use in the morning to ensure your skin is protected and looking its healthiest. Due to the small size of salicylic acid molecules, it is an acid that is able to reach the deepest parts of the skin. While this is effective at keeping skin clear, it also increases the risk of irritation and photosensitivity. Therefore, many people prefer to use powerful BHAs in their evening routine without exposure to UV rays, pollution, or harsh weather. Warning: If you avoid using sunscreen every day, none of these ingredients will do what your skin needs. The combination of chemical peels and powerful ingredients increases the risk of further damage to the skin’s surface. Use SPF 50 every day to keep your skin protected and your lipid barrier healthy, even on cloudy days, keeping your skin in top condition.
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