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Melasma Cream or Melasma Serum?
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Melasma Cream or Melasma Serum?

1 March 2025


Melasma Cream or Melasma Serum?




Melasma creams and serums are used to treat dark spots and uneven skin, otherwise known as hyperpigmentation. Melasma creams and serums can be used on the face, chest, arms or other parts of the body.



These skin care products to lighten skin have different types of skin Lightening ingredients including retinol, adapalene, hydroquinone, tretinoin, Vitamin C and natural ingredients.




If you have melasma on your face, it is important to use the correct melasma skincare routine every day to even your skin tone and encourage healing and clearing.



Here we take a look at the best melasma creams and melasma serums for your skin type.




Step 1 is to know your skin type!



16 Bauman Skin Types




What Is Better for Melasma: A Melasma Cream or a Melasma Serum?



There are a variety of melasma creams and serums available, but what’s best for you depends on your Baumann Skin Type®. Oily skin types do better with serums while dry skin types needs creams. Sensitive skin types with melasma need soothing anti-inflammatory ingredients. Aging skin needs antiaging ingredients and ingredients to protect skin from pollution.




The easiest way to figure out which melasma ingredients to look for in creams and serums that will treat all of your skin concerns is to take the quiz and let our dermatologists guide you.



Take the Quiz




what skin types need a melasma cream



Dry skin types usually prefer an anti-melasma cream while oily skin types prefer an anti-melasma serum. The best melasma product for your skin type depends upon any skin conditions you might have, such as dehydration, inflammation, and skin aging.




Once you take the Skin Type Quiz, our software will personalize a skincare routine with the best serum or cream for melasma that suits your skin type. You can choose the best skincare brands for your budget, and we will tell you the exact skincare routine steps and when to use your melasma cream. Whether you want to save money or splurge, we will guide you with our dermatologist-recommended skincare routines.



Best treatments for melasma in dry skin




What Are the Best Melasma Creams for Dry Skin?



Melasma creams for dry skin types may have fatty acids to hydrate the skin. If they do not, you can use a barrier repair moisturizer on top of our melsama cream.




PCA Skin Vitamin B3 Brightening Serum



$128.00




Add to Cart



PCA Skin Pigment Gel HQ Free




$95.00



Add to Cart




Replenix Pigment Correcting Brightening Cream



$44.00




Add to Cart



Revision Skincare C+ Correcting Complex 30%




$116.00



Add to Cart




ClarityRx Let There Be Light Powerful Lightening Serum



$110.00



Add to Cart

Medature Hydro Bright Treatment

$45.00

Add to Cart

ISDIN Pigment Expert

$48.00

Out of Stock

Neocutis PERLE Skin Brightening Cream

$121.00

Add to Cart

Obagi Nu-Derm Blend Fx (Hydroquinone Free)

$119.00

Add to Cart

Obagi Nu-Derm Clear Fx (Hydroquinone Free)

$119.00

Add to Cart

PCA Skin Vitamin B3 Brightening Serum

$128.00

Add to Cart

PCA Skin Pigment Gel HQ Free

$95.00

Add to Cart

Replenix Pigment Correcting Brightening Cream

$44.00

Add to Cart

Revision Skincare C+ Correcting Complex 30%

$116.00

Add to Cart

ClarityRx Let There Be Light Powerful Lightening Serum

$110.00

Add to Cart

Medature Hydro Bright Treatment

$45.00

Add to Cart

ISDIN Pigment Expert

$48.00

Out of Stock

Neocutis PERLE Skin Brightening Cream

$121.00

Add to Cart

Obagi Nu-Derm Blend Fx (Hydroquinone Free)

$119.00

Add to Cart

Obagi Nu-Derm Clear Fx (Hydroquinone Free)

$119.00

Add to Cart

PCA Skin Vitamin B3 Brightening Serum

$128.00

Add to Cart

PCA Skin Pigment Gel HQ Free

$95.00

Add to Cart

Replenix Pigment Correcting Brightening Cream

$44.00

Add to Cart

Revision Skincare C+ Correcting Complex 30%

$116.00

Add to Cart

ClarityRx Let There Be Light Powerful Lightening Serum

$110.00

Add to Cart

Medature Hydro Bright Treatment

$45.00

Add to Cart

ISDIN Pigment Expert

$48.00

Out of Stock

Neocutis PERLE Skin Brightening Cream

$121.00

Add to Cart

Obagi Nu-Derm Blend Fx (Hydroquinone Free)

$119.00

Add to Cart

Obagi Nu-Derm Clear Fx (Hydroquinone Free)

$119.00

Add to Cart

What Are the Best Melasma Serums for Oily Skin?

Serums are better for oily skin types because they are lighter. If you have oily skin and you choose to use a melasma cream, you can skip a moisturizer.

Obagi Nu-Derm FX Starter System – Normal to Oily

$480.00

Add to Cart

PCA Skin Vitamin B3 Brightening Serum

$128.00

Add to Cart

PCA Skin Pigment Gel HQ Free

$95.00

Add to Cart

PCA Skin Pigment Gel PRO

$128.00

Add to Cart

Biopelle Brightening KNR Serum

$126.00

Add to Cart

ClarityRx Let There Be Light Powerful Lightening Serum

$110.00

Add to Cart

Medature Hydro Bright Treatment

$45.00

Add to Cart

ISDIN Pigment Expert

$48.00

Out of Stock

La Roche-Posay Glycolic B5 Serum

$44.99

Add to Cart

Obagi Nu-Derm Clear Fx (Hydroquinone Free)

$119.00

Add to Cart

Obagi Nu-Derm FX Starter System – Normal to Oily

$480.00

Add to Cart

PCA Skin Vitamin B3 Brightening Serum

$128.00

Add to Cart

PCA Skin Pigment Gel HQ Free

$95.00

Add to Cart

PCA Skin Pigment Gel PRO

$128.00

Add to Cart

Biopelle Brightening KNR Serum

$126.00

Add to Cart

ClarityRx Let There Be Light Powerful Lightening Serum

$110.00

Add to Cart

Medature Hydro Bright Treatment

$45.00

Add to Cart

ISDIN Pigment Expert

$48.00

Out of Stock

La Roche-Posay Glycolic B5 Serum

$44.99

Add to Cart

Obagi Nu-Derm Clear Fx (Hydroquinone Free)

$119.00

Add to Cart

Obagi Nu-Derm FX Starter System – Normal to Oily

$480.00

Add to Cart

PCA Skin Vitamin B3 Brightening Serum

$128.00

Add to Cart

PCA Skin Pigment Gel HQ Free

$95.00

Add to Cart

PCA Skin Pigment Gel PRO

$128.00

Add to Cart

Biopelle Brightening KNR Serum

$126.00

Add to Cart

ClarityRx Let There Be Light Powerful Lightening Serum

$110.00

Add to Cart

Medature Hydro Bright Treatment

$45.00

Add to Cart

ISDIN Pigment Expert

$48.00

Out of Stock

La Roche-Posay Glycolic B5 Serum

$44.99

Add to Cart

Obagi Nu-Derm Clear Fx (Hydroquinone Free)

$119.00

Add to Cart

best melasma serums for oily skin types

What Are the Best Melasma Serums for Combination Skin?

(We don’t believe in the combination skin type by the way- read more here).

SkinCeuticals Discoloration Defense is a good melasma treatment for skin that is oily in the T-zone. If you want a lightweight hyperpigmentation serum this one contains kojic acid, tranexamic acid, and vitamin B3 and is clinically proven to remove dark spots. Vitamin B3 is a popular skincare ingredient that can reduce dark spots on the skin and even skin tone. It also soothes skin and reduces inflammation.

Kojic acid lightly exfoliates the skin and provides the same benefits as vitamin B3. Tranexamic acid is a new ingredient in topical melasma creams and serums. This new skin lightening ingredient treats hyperpigmentation and brightens the skin. Tranexamic acid is most effective as a prescription melasma pill that you take orally, but many companies are now putting it in topical skin care products.

retinol

Retinol Serum For Melasma

Retinoids are great for melasma because they exfoliate and inhibit tyrosinase to lower pigment production.

However, you must use them properly so you do not get a retinoid dermatitis which can lead to post inflammatory hyperpigmentation. This is why Retin A can make melasma worse!

These are the retinoids used to treat melasma:

Tretinoin 0.025%, 0.05% and 0.1%(Retin A)

Adapalene (Differin)

Tazarotene

Retinol

best ingredients for treating melasma

Natural Melasma Creams

Plant extracts with skin lightening, anti-inflammatory, and antioxidant properties can be used in vegan, natural and clean creams to treat melasma.

Silymarin for Melasma

Silymarin is a natural ingredient found in melasma creams. A double-blind placebo-controlled study investigated the safety and efficacy of topical Silymarin (SM) cream in to treat melasma. The clinical and histopathology observations significantly improved in the Silymarin-treated groups. Clinically, patients showed significant pigment improvement and lesion size reduction, starting from the first week of Silymarin treatment. The treatment was well-tolerated with no observed side effects, and all patients reported being fully satisfied with the results. These findings suggest that Silymarin is a promising, safe, and effective treatment for melasma, with results indicating a dose-dependent improvement in the condition. (9)

Silymarin shows strong free radical-scavenging activity, which is several times greater than that of vitamin E. It prevents lipid peroxidation and provides significant protection against UVB-induced depletion of catalase activity.

Silymarin can effectively neutralize harmful biochemical reactions triggered by free radicals and reactive oxygen species (ROS), thereby strengthening the skin’s cellular antioxidant status. This antioxidant capacity is pivotal in protecting skin cells from the oxidative stress induced by solar UV radiation, which is a known factor in skin aging, melanogenesis, and carcinogenesis.

Research has revealed that Silymarin, and specifically one of its main components, 2,3-dehydrosilybin (DHSB), possesses UVA protection properties. Silymarin and its flavonolignans were found to inhibit the activities of collagenase and elastase, two enzymes that play a role in skin aging. Of the flavonolignans studied, DHSB was identified as the most potent.

Silymarin has been shown to inhibit l-DOPA oxidation activity of tyrosinase, the rate-limiting melanogenic enzyme. This decreases production of melanin.

melanin

China Camellia

Research has shown that the extract of China Camellia can effectively inhibit tyrosinase activity and the proliferation of melanocytes, both of which are vital for the control of pigmentation. (8) In addition, camellianin A, a component of China Camellia, is known for its potent antioxidant activity. Since oxidative stress has been linked to hyperpigmentation, the antioxidant properties of China Camellia, along with its ability to inhibit melanogenesis, are likely significant factors in its efficacy in improving pigmentation in melasma when used as a component of natural and vegan creams.

Prinsepia utilis oil

Prinsepia utilis oil may be a good natural ingredient in melasma treatments due to its ability to improve epidermal permeability barriers. Research suggests that Prinsepia utilis can stimulate the production of epidermal lipids, including ceramides, which are major components of lamellar lipids in the stratum corneum. A defective epidermal permeability barrier has been proposed to contribute to the development of melasma, so the Prinsepia utilis-induced improvement in this barrier might be an additional mechanism by which the cream of herbal mixture positively affects melasma.

Portulaca oleracea

Portulaca oleracea, often referred to as purslane, is another herbal ingredient in melasma creams. A study (8) showed that the treatment with this herb in a mixture of herbs in a cream led to a decrease in the density of inflammatory cells in the melasma lesion. This outcome may be attributable to the anti-inflammatory and antioxidant properties of portulaca oleracea. Melasma is known to be characterized by inflammatory cells infiltrating the superficial dermis and capillaries, and we know that inflammation leads to hyperpigmentation, so Portulaca oleracea’s soothing abilities may help treat melasma naturally.

Sanchi (Panax Notoginseng)

Sanchi, also known as Panax notoginseng has panax notoginseng saponins (PNS) that have anti-inflammatory effects and antioxidant activity. This herb has been used in an herbal cream to treat melasma . (8)

vitamin c

Vitamin C for Melamsa

Vitamin C should be used with other tyrosinase inhibitors and during a tyrosinase inhibitor holiday. You can learn more about which Vitamin C to choose to use for melasma at this link.

Melasma Treatment Skincare Routine

Once you have a personalized skincare routine to treat melasma, you need to use it every day as prescribed. The skin constantly produces melanin, and you must be consistent with your melasma skincare regimen to get the best results. Your skin becomes accustomed to the skin lightening ingredients, and they will stop working after a few months. Regular use of your melasma skincare regimen will help clear dark spots on the skin before the skin-lightening ingredients stop working.

Use melasma cream consistently in a daily routine

Melasma Treatment Skincare Routines: Treatment Regimens and Maintenance Regimens

You need two different melasma treatment skincare routines to treat melasma. The Melasma Treatment Regimen is used for 3 months, and the Melasma Maintenance Regimen is used for one month. You should cycle between these two to keep melasma under control.

Why Do I Need to Take A Holiday From My Melasma Cream?

Melasma treatments tend to stop working after three to four months. You want to get as much out of the melasma treatment before this happens, so use your regimen consistently every day for the first four months. This is called the “treatment regimen” because treats dark spots on the face. You can learn more about the best skincare routine for melasma here.

Do I Apply My Sunscreen Before or After My Melasma Cream or Melasma Serum?

You should always apply your melasma serum or melasma cream before an SPF.

How to Make Melasma Creams And Melasma Serums Work Faster

Skin lightening creams and serums work faster to treat melasma when used properly. Understanding the causes of melasma and following tips to make it go away faster is an important part of melasma treatment.

Use an SPF every day to protect yourself from the sun with any skincare routine. This is even more important if you are undergoing melasma treatment to prevent any new dark spots from forming. Tinted sunscreens are our favorite sunscreens for melasma because they have iron oxides that help block blue light. here are some of our favorite mineral sunscreens:

Replenix Tinted Mattifying Face Sunscreen SPF 30

$46.00

Out of Stock

SkinCeuticals Physical Fusion UV Defense SPF 50

$42.00

Add to Cart

Derma Made SPF 50 Tinted Moisturizer

$34.00

Add to Cart

Alastin HydraTint Pro Mineral Broad Spectrum Sunscreen SPF 36

$76.00

Add to Cart

EltaMD UV Luminous Broad Spectrum SPF 41

$41.00

Add to Cart

EltaMD UV Physical Broad-Spectrum SPF 41 Tinted

$44.00

Out of Stock

La Roche-Posay Anthelios Mineral Light Fluid Sunscreen SPF 50

$36.99

Add to Cart

Obagi Sun Shield Tint Broad Spectrum SPF 50 Cool

$59.00

Add to Cart

Obagi Sun Shield Tint Broad Spectrum SPF 50 Warm

$59.00

Add to Cart

PCA Skin Sheer Tint Broad Spectrum SPF 45

$56.00

Add to Cart

Replenix Tinted Mattifying Face Sunscreen SPF 30

$46.00

Out of Stock

SkinCeuticals Physical Fusion UV Defense SPF 50

$42.00

Add to Cart

Derma Made SPF 50 Tinted Moisturizer

$34.00

Add to Cart

Alastin HydraTint Pro Mineral Broad Spectrum Sunscreen SPF 36

$76.00

Add to Cart

EltaMD UV Luminous Broad Spectrum SPF 41

$41.00

Add to Cart

EltaMD UV Physical Broad-Spectrum SPF 41 Tinted

$44.00

Out of Stock

La Roche-Posay Anthelios Mineral Light Fluid Sunscreen SPF 50

$36.99

Add to Cart

Obagi Sun Shield Tint Broad Spectrum SPF 50 Cool

$59.00

Add to Cart

Obagi Sun Shield Tint Broad Spectrum SPF 50 Warm

$59.00

Add to Cart

PCA Skin Sheer Tint Broad Spectrum SPF 45

$56.00

Add to Cart

Replenix Tinted Mattifying Face Sunscreen SPF 30

$46.00

Out of Stock

SkinCeuticals Physical Fusion UV Defense SPF 50

$42.00

Add to Cart

Derma Made SPF 50 Tinted Moisturizer

$34.00

Add to Cart

Alastin HydraTint Pro Mineral Broad Spectrum Sunscreen SPF 36

$76.00

Add to Cart

EltaMD UV Luminous Broad Spectrum SPF 41

$41.00

Add to Cart

EltaMD UV Physical Broad-Spectrum SPF 41 Tinted

$44.00

Out of Stock

La Roche-Posay Anthelios Mineral Light Fluid Sunscreen SPF 50

$36.99

Add to Cart

Obagi Sun Shield Tint Broad Spectrum SPF 50 Cool

$59.00

Add to Cart

Obagi Sun Shield Tint Broad Spectrum SPF 50 Warm

$59.00

Add to Cart

PCA Skin Sheer Tint Broad Spectrum SPF 45

$56.00

Add to Cart

16 Bauman Skin Types

Make it easy on yourself- take the quiz and we will show you which melasma cream brands are best for your skin type. You can pick and choose based on price, brand or other preferences. We don’t care what brand you buy- as long as you buy something that is going to work for YOU!

DQH Knowledge drop: In your 20s, your skin cell turnover decreases. (Cell turnover is a key component in keeping your skin youthful.) You know what else slows down? Your collagen production. Starting in your 20s, collagen decreases by about 1 percent per year. Should you want to prevent fine lines and wrinkles, start by eliminating behaviors that contribute to premature aging. “If it’s bad for you, it’s bad for your skin,” says dermatologist Michel Somenek. “Cigarette smoking reduces blood flow to the skin and causes premature wrinkling and a dull skin texture. Making the repeated pursed motion to inhale can also cause smoker’s lines. Alcohol and recreational drugs are toxins for the skin that damage its cellular structure and DNA,” Somenek tells us. “The faster you eliminate vices while you are young, the better chance your skin and body have to recuperate.” Also, adopting an anti-aging routine in your 20s is key. After all, the best offense is a good defense. We spoke to Somenek and experts Joshua Ross and Audrey Kunin to find out more. Keep reading for the best anti-aging products for your 20s, according to skincare professionals. Sunscreen “We all know that the sun is the number one cause of skin aging and starting the prevention in your 20s is very important,” Ross says. “The majority of your sun damage won’t start to appear until you’re in your 30s, so don’t wait until you see it surface or you’ll be behind the curve. Stay ahead of it with a good-quality zinc-based sunscreen worn daily.” Farmacy Green Defense Daily Mineral Sunscreen An invisible sunscreen with SPF 30, plus botanical extracts meant to protect skin with tons of antioxidants. Bonus: It’s clean and fine to use under makeup. Bareminerals Complexion Rescue™ Tinted Moisturizer Broad Spectrum SPF 30 Although we recommend you use your SPF and moisturizer separately, we also understand moments when you don’t have time or energy for that extra step. For those times, this bareMinerals moisturizer is a great thing to have on hand. Vitamin C Serum “A great introduction to anti-aging is to start with a vitamin C serum in your morning skincare routine,” Ross says. “It’s a powerful antioxidant that will neutralize free radicals and brighten the skin.” He adds that it’s a great way to counteract the effects of the sun’s harmful rays, which, as previously mentioned, are among the biggest causes of premature aging. Drunk Elephant C-Firma™ Vitamin C Day Serum The Drunk Elephant C-Firma is a lightweight serum that promises to give skin a glow by combining the brightening powers of vitamin C with ferulic acid, l-ascorbic acid, and vitamin E. The included sodium hyaluronate is meant to replace hydration loss, so you shouldn’t have to deal with any irritation. Sunday Riley C.E.O. Rapid Flash Brightening Serum This potent serum is jam-packed with vitamin C (15 percent, to be exact), which means it’s a potential superstar at both brightening skin and dousing it in antioxidants. Peptides Using peptides on your skin has many benefits, says Somenek. “The skin barrier is what defends the body against pollution, UV rays, bacteria, and toxins. It can be damaged by several everyday factors. Using topical peptides aids in building a stronger barrier,” he says. “Peptides comprise elastic fibers, which are a type of protein. These fibers help to make skin appear taut and firm. Peptides can also help repair damaged skin, relieve inflammation, and even out skin tone. Some peptides can kill acne-causing bacteria that is common in 20-somethings.” Kunin agrees, saying, “Peptides are an excellent entry point for supporting collagen.” She recommends looking for face and eye treatments that contain these collagen-boosting powerhouses. Charlotte Tilbury Magic Eye Rescue Cream This Charlotte Tilbury super-emollient eye cream has a base of coconut oil and shea butter (read: it’s incredibly hydrating). Botanicals plus peptides are meant to help reduce dark circles and boost collagen, respectively. This creamy moisturizer serves up potent collagen-boosting peptides and pycnogenol, and antioxidant-rich vitamin C. “Instead of sitting on top of the skin, peptides penetrate the outer layer so they go deep. The ‘signals’ they send tell the cells to produce elastin and collagen, which are needed for youthful-looking skin,” explains Somenek. At-Home Peel Pads Remember that skin cell turnover fiasco we talked about earlier? One way to help support it is by exfoliating. “Exfoliation is important to help keep skin fresh and luminous,” Kunin says. She recommends using at-home peel pads as an easy and effective way to exfoliate. “The goal in your 20s is to fight the slowing pace of cell turnover. It is wise to use products that gently exfoliate, yet still remove oil and other impurities. Products that have Alpha Hydroxy Acids (AHA) or Beta Hydroxy Acids (BHA) are a good choice.” According to Somenek, you should only exfoliate two to three times a week. “People of all ages are guilty of over-exfoliating and that can be too much of a good thing,” he says. Dermadoctor Kakadu C Intensive Vitamin C Peel Pad A few swipes of this Derma Doctor powerful peel pad promise to leave your skin glowing and smooth, thanks to the seven (yes, seven) types of chemical exfoliants, including AHA and BHA. It also contains vitamin C via Kakadu plum extract for added brightening and antioxidant protection. KEY INGREDIENTS Kakadu plum extract is sourced from the Kakadu plum, a fruit grown in northern Australia. It contains vitamin C, which restores the skin’s natural barrier, increases collagen production, and soothes irritation. Dr. Dennis Gross Skincare Alpha Beta® Universal Daily Peel Pads These are the gold standard of peel pads, with a cult following and over 900 five-star reviews on Sephora. They’re easy to use and contain a blend of anti-aging exfoliating acids. Emollient Night Cream “In your 20s, you need to start upping the hydration in your skincare routine. You may have been cautious of over-moisturizing because of acne in your teens, but as you enter your 20s, your skin transitions and becomes drier,” Ross says. “I recommend an emollient night cream added into your evening skincare regimen.” “Twenty-somethings need to make sure that they are not using creams that will clog their pores and cause excess oil production,” says Somenek. Opt for non-comedogenic products. Cerave Skin Renewing Night Cream One great choice is the CeraVe Skin Renewing Night Cream, which is a non-comedogenic night cream that leaves skin soft and glowy. It combines the moisturizing powers of ceramides and hyaluronic acid. RoC Retinol Correxion Max Hydration Creme “The best night cream ingredients contain retinol, benzoyl peroxide, and/or salicylic acid or hyaluronic acid. The goal is to moisturize, yet remove excess oil,” says Somenek. This Roc Retinol Correxion cream fits the bill as it contains both hyaluronic acid and retinol so it promises to moisturize while also being non-comedogenic.
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