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Omega-3s and the Mediterranean Diet: A Potential Solution for Clearer Skin
Beauty

Omega-3s and the Mediterranean Diet: A Potential Solution for Clearer Skin

31 March 2025


Could Omega-3s and the Mediterranean Diet Be the Key to Clearer Skin?




A new study found that consuming an omega-3 supplement and following the Mediterranean diet could improve acne.



Both omega-3s and the Mediterranean diet reduce inflammation and regulate hormones associated with acne, targeting the root causes of the condition.




More research is needed to establish a causal effect, but the results show that dietary interventions could help manage acne beyond just prescription drugs, researchers said.



Sticking to a certain diet and supplement routine may be able to boost a person’s skin health, according to new research.




A study published on July 10 in the Journal of Cosmetic Dermatology found that people with mild-to-moderate acne saw their symptoms improve after they took an omega-3 supplement and followed the Mediterranean diet.1



Over the course of 16 weeks, researchers in Germany followed 58 women and two men, who were, on average, 26 years old. At the beginning of the study, about 98% of the participants were deficient in omega-3. None of them were taking prescription drugs to manage acne.




The researchers’ goal was to see if diet could be a key contributor to participants’ acne, since processed foods, refined sugars, saturated fats, cow’s milk, and dairy products have been tied to the development of acne.1 They hoped to investigate whether people could improve their acne if they reduced their consumption of some of these foods while also increasing intake of fatty acids.



To this end, participants followed the Mediterranean diet and took an oral algae-derived omega-3 supplement. They met with researchers four times over the course of the study.




In the end, 42 of the 60 patients said the changes improved the severity of their acne, and researchers noted significant reductions in the number of inflammatory and non-inflammatory lesions. And overall, the participants’ omega-3 levels went up.1



The results of the study show that dietary interventions could be a useful tool for managing acne beyond just prescription drugs.1




“Lifestyle interventions, including dietary recommendations, should not be considered in opposition to prescription medications, but rather as a valuable adjunct to any modern acne treatment plan,” study author Anne Guertler, MD, a dermatologist and researcher at Ludwig Maximilian University of Munich, said in a press release.2



Here’s what experts had to say about the connection between the Mediterranean diet, omega-3s, and acne, plus what to know before you start tweaking your diet in the name of skin health.




Why Diet and Omega-3 Consumption Can Affect Your Skin



Acne is an inflammatory skin condition that occurs “due to increased oil production from hormonal changes, clogged pores from dead skin cells, and inflammation caused by the bacteria Cutibacterium acnes,” Victoria Billero, MD, dermatologist and assistant professor at Tufts University School of Medicine, told Health.




Essentially, hair follicles become clogged with oil and skin cells, leading to blockages or pimples.3



There are a number of factors that can make someone more prone to acne, including “hormones, stress, lifestyle, microbiome, and immune function,” Dendy Engleman, MD, a board-certified dermatologic surgeon at Shafer Clinic Fifth Avenue, told Health.




However, what you eat can also impact acne—specifically, certain foods can exacerbate the condition, including dairy products or high-glycemic foods, which spike blood sugar.45



“Some foods may contribute to acne by influencing oil production and microbiome health,” Engleman said. “On the other hand, a diet rich in nutrients can support overall skin health.”




This is why the Mediterranean diet could be beneficial for people with acne—many of the foods in the diet, such as vegetables and nuts, tend to have a low glycemic index, plus the diet has anti-inflammatory properties.



What Is the Mediterranean Diet?




The Mediterranean diet is based on the traditional eating habits of countries bordering the Mediterranean Sea. It usually includes a high intake of vegetables, fruits, nuts, legumes, and olive oil, a moderate intake of fish, meat, and dairy products, and a low intake of sweets. The diet has been associated with a lower risk of cancer, heart disease, and cognitive issues.6



“The diet emphasizes whole foods, rich in nutrients that support skin health, while limiting processed foods,” Engelman said. “The diet’s focus on fruits, vegetables, whole grains, fish, and healthy fats can also potentially reduce inflammation and regulate hormones associated with acne, targeting many of the key root causes of the condition.”




The Mediterranean diet is also high in fatty acids such as omega-3, which previous research has linked to improvements in acne and other skin conditions.789



“Omega-3s have anti-inflammatory properties, which can help reduce inflammation associated with acne,” said Engleman. “Having a diet low in omega-3s may contribute to acne because a deficiency can result in higher levels of inflammation and an imbalance in the skin’s oil production.”




Using Food to Take Care of Your Skin



Despite the study’s findings, more research is needed to determine how omega-3s and the Mediterranean diet affect acne. With the way the study was designed, it’s not clear whether it was dietary changes, increases in omega-3 levels, or some other factor that specifically caused participants’ acne to improve.1




The study had other limitations as well; the cohort was overwhelmingly female and relatively small, plus researchers relied on surveys to assess participants’ dietary habits, which opens up the door for recall bias.1



It’s too soon to definitively say that increasing omega-3 intake and sticking to the Mediterranean diet can clear up your acne. But making these dietary changes can still be helpful for reducing inflammation and boosting health more generally, in addition to the potential for improved skin.1




“It is important that individuals focus on a balanced diet consisting of nutrient-rich foods if they are looking to improve their skin health,” Engelman said.



In particular, the following steps could be helpful in improving acne and overall health, she added:




Increasing intake of fruits, vegetables, and whole grains for antioxidants and fiber



Adding healthy fats—especially omega-3s from sources such as fish, nuts, and seeds—into your diet




Staying hydrated


Limiting consumption of highly processed or sugary foods or beverages

Eating low-glycemic foods to help regulate blood sugar

According to Billero, choosing foods that will stabilize blood sugar levels is one of the best ways to see acne improvements.

“I tell my patients with acne that one thing they can do to help their skin through diet is to pair their carbohydrates with a healthy fat like avocado, fish, olive oil, nuts, or seeds,” she explained. “These healthy fats slow digestion so the sugars aren’t absorbed too quickly into the bloodstream, altering hormone levels.”

But if dietary changes or over-the-counter treatments for acne aren’t working, it’s worth seeing a dermatologist to discuss other options, experts said.

“There are other factors at play in acne, including genetics, environmental exposures, and some medications, so focusing on diet alone may not be enough for some people,” Billero explained.

DQH Can I use salicylic acid first and then vitamin C? It’s easy to create a skincare routine, but knowing how to use it is another thing entirely. In most cases, if you’re not getting the desired skin results, it could be due to the layering of conflicting ingredients. So, is it possible that salicylic acid and vitamin C are such ingredients? Or are these active ingredients the duo that’s been missing from your skincare routine? If you want answers, stick around because today we are going to explain the benefits of salicylic acid and vitamin C and how they can be used in your daily life. What are the benefits of salicylic acid for skin? Salicylic acid is one of the most commonly used beta hydroxy acids and is favored by many people with oily, acne-prone skin. This acid is derived from willow bark, and unlike its water-soluble relatives (called alpha-hydroxy acids), salicylic acid is oil-soluble, which means it can penetrate deeper into the lower layers of the skin. Once it reaches the lower layers, it can help unclog pores of excess sebum, dirt, bacteria, debris, and impurities. This results in clearer skin tones and greater definition. Not only does salicylic acid benefit the underlying layers, but the outer surface of the skin benefits as well. When applied to the skin, salicylic acid removes the buildup of dead skin cells. This is accomplished by breaking the bonds that hold dead cells to the surface. Over time, this can cause the complexion to look dull and prone to acne, blackheads, and other blemishes. If you’d like to learn more about salicylic acid and how it can improve your skin, check out this dedicated blog post from a beauty insider. What are the benefits of vitamin C for skin? Vitamin C is considered one of the most powerful antioxidants, which means it is very effective at fighting free radicals and preventing them from causing further skin damage. Examples of free radicals include pollution, central heating, UV rays and harsh climate. They attack proteins, fats and cell membranes as soon as they come into contact with the skin, causing signs of premature aging such as fine lines and wrinkles as well as hyperpigmentation, flaky patches of skin and loss of elasticity. Many people usually prefer to use vitamin C in their morning routine as this ingredient gives the complexion a radiant glow. You’ll also find that vitamin C can target areas of hyperpigmentation, plumping the skin and reducing the appearance of fine lines and wrinkles. The thing about vitamin C is that there are a lot of outdated studies going back to the 1950s that describe vitamin C as an unstable skin component. Thanks to improvements in modern technology, this is no longer the case as all products now contain a stable form of vitamin C. Visit The Beauty Insider to learn more about vitamin C. So please check out our blog post. Can I use salicylic acid first and then vitamin C? Yes, you absolutely can. In fact, it’s thought that using salicylic acid before using vitamin C ensures it penetrates faster and works faster. This is an efficient way to utilize two power sources, and the reason has to do with pH. For example, the skin’s natural pH is about 4.7, making it slightly acidic. Salicylic acid and vitamin C are also both acidic, and you’ll find that vitamin C is absorbed quickly into the skin. Therefore, using salicylic acid beforehand can increase the acidity of the skin and allow vitamin C to penetrate into the skin faster. While this is considered an effective way to combine two powerful ingredients, you need to be aware of your skin type and how it reacts to certain active ingredients. Even people with perfect, normal skin can experience skin sensitivity and irritation. Therefore, always consult a doctor or dermatologist before using any new products on your skin. It’s also important to follow skin application rules. In this case, you need to use the product correctly to ensure you get the best results for your skin. If you’re not sure what I mean, the basic rule for skin is to start with the thinnest consistency and work your way up to the thickest consistency. This prevents a barrier from forming on the surface, preventing other active ingredients from penetrating the skin. Can I use salicylic acid at night and vitamin C in the morning? Yes, absolutely, this is considered the most effective way to get returns without any adverse side effects. This is because there is enough time between applications to ensure that the skin’s pH levels return to balance. You’ll also find that Vitamin C is rich in antioxidants and is perfect for use in the morning to ensure your skin is protected and looking its healthiest. Due to the small size of salicylic acid molecules, it is an acid that is able to reach the deepest parts of the skin. While this is effective at keeping skin clear, it also increases the risk of irritation and photosensitivity. Therefore, many people prefer to use powerful BHAs in their evening routine without exposure to UV rays, pollution, or harsh weather. Warning: If you avoid using sunscreen every day, none of these ingredients will do what your skin needs. The combination of chemical peels and powerful ingredients increases the risk of further damage to the skin’s surface. Use SPF 50 every day to keep your skin protected and your lipid barrier healthy, even on cloudy days, keeping your skin in top condition.
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