Pyrroloquinoline quinone (PQQ) In Skin Care

Skin care enthusiasts like me are always on the hunt for the next big ingredient that promises glowing, healthy skin. In my opinion as a dermatologist, Pyrroloquinoline Quinone, or PQQ, might become a new star in the skin care world. This blog will dive into what PQQ is, why it’s interesting, its benefits, safety, and how it stacks up against Coenzyme Q10 (CoQ10). We’ll also discuss which Baumann Skin Types can benefit from PQQ and share some reviews. To find your Baumann Skin Type, take our quiz for free today with the button below! (Taking the quiz also earns you rewards point for our store!)

Antioxidant benefits comparable to CoQ10

Boosts cellular energy by helping produce more mitochondria

Anti-inflammatory and has barrier repair functions

Not commonly used in topical formulas (too new of an ingredient)

Naturally occurring compound in both plants and animals

What is Pyrroloquinoline Quinone (PQQ)?

Pyrroloquinoline Quinone (PQQ) is a small aromatic molecule found in various foods and even in our bodies. Scientists classify PQQ as a nutrient that helps with energy production and protection against cell damage. It plays a crucial role in our body’s energy management and defense systems.

Why is PQQ Interesting?

PQQ is fascinating because it acts like a protector and energy booster for our cells. It shields cells from damage caused by harmful molecules called free radicals and supports the creation of new mitochondria. Mitochondria are like tiny batteries that power our cells. More and better-functioning mitochondria mean healthier and more energetic cells. This can help our skin look younger.

Another interesting feature of PQQ is that it is still rare to find in topical skin care products. Most studies have been about its use in supplements. So, if you’re looking for products that are very much like PQQ, here are some of the best ones:

The Benefits of PQQ

PQQ has many functions and potential benefits in skin care. Science on this ingredient is still developing, but for now, some of the most notable skin care benefits of PQQ are:

Powerful Antioxidant – PQQ acts as a powerful antioxidant, which means it protects your cells from damage caused by free radicals. Free radicals are unstable molecules that can harm cells, leading to aging and various skin problems. By neutralizing these harmful molecules, PQQ helps keep your skin looking youthful and healthy. Studies have shown that PQQ can neutralize a wide range of free radicals, including those generated by UV radiation and pollution.

Boosts Cellular Energy – PQQ helps increase the number of mitochondria in cells. Mitochondria are responsible for producing energy (ATP) in cells. More mitochondria mean more energy, which helps skin cells repair themselves faster and stay healthy. This can result in a brighter and healthier complexion. PQQ activates certain genes that promote mitochondrial biogenesis, leading to increased energy production within the skin cells.

Reduces Inflammation -Inflammation can cause redness, swelling, and discomfort in the skin. PQQ has anti-inflammatory properties that help reduce these symptoms. PQQ reduces inflammation by lowering the levels of molecules that promote inflammation, such as interleukin-6 (IL-6) and C-reactive protein (CRP). This makes it beneficial for people with conditions like acne and rosacea.

Improves Skin Barrier – The skin barrier is like a wall that keeps moisture in and harmful substances out. PQQ strengthens this barrier by promoting the production of ceramides and other lipids that are essential for maintaining a healthy skin barrier. This helps your skin stay hydrated and protected against environmental damage like pollution and UV rays. Improved skin barrier function reduces transepidermal water loss (TEWL) and enhances overall skin hydration.

PQQ Side effects

While PQQ is generally safe, some people might experience mild side effects like stomach discomfort or headaches, especially if they take high oral doses. These side effects are rare, but it’s always a good idea to start with a small amount and see how your body reacts.

Organizations like the National Institute of Health also classify Pyrroloquinoline quinone as a safe ingredient in skin care

PQQ Supplements

PQQ is available in supplement form and can be taken orally. Studies show that taking PQQ supplements can improve various health markers, including reducing inflammation and boosting mitochondrial function. For skin benefits, typical doses range from 10 to 20 mg per day. However, it’s best to consult with a healthcare provider before starting any new supplement to ensure it’s right for you.

PQQ vs CoQ10

Both PQQ and CoQ10 are popular for their skin benefits, but they have some subtle differences. These differences include:

Structure and Function – PQQ helps create new mitochondria, while CoQ10 helps existing mitochondria work better. Think of PQQ as increasing the number of energy factories in your cells, while CoQ10 improves the efficiency of the existing factories.

Antioxidant power – Both PQQ and CoQ10 are powerful antioxidants. However, PQQ is often highlighted for its ability to neutralize a broader range of free radicals more effectively. CoQ10 is still excellent for protecting skin cells from oxidative stress and is widely used in skin care for its proven benefits.

Mitochondrial support – While both PQQ and CoQ10 support mitochondrial health, PQQ’s ability to create new mitochondria gives it an edge in boosting overall cellular energy. This increased energy production helps skin cells stay healthy and repair themselves more effectively.

Overall Benefits – Both PQQ and CoQ10 can improve skin health. PQQ’s antioxidant and anti-inflammatory properties make it effective for protecting against environmental damage and calming irritated skin. CoQ10 is well-known for maintaining skin collagen and reducing the appearance of fine lines and wrinkles by supporting energy production in skin cells.

Which skin types can use PQQ?

The Baumann Skin Typing System classifies skin into 16 different types based on skin barrier function, sensitivity, aging, and pigmentation. Here’s who can benefit the most from PQQ:

Dry skin Types – By aiding in the synthesis of essential lipids like ceramides, this ingredient can help dry skin types hold on to the moisture already in their skin.

Sensitive Skin Types – Since this ingredient shuts down certain inflammation pathways, it is a good choice as a soothing, anti-inflammatory ingredient for sensitive skin types.

Wrinkle Prone Skin Types – Wrinkle prone skin types can benefit from the antioxidant and cell energizing properties of PQQ. While it won’t halt aging, it can play a supporting role in the right anti-aging regimen.

To find out if you’re one of those skin types, take our quiz for free today!

Conclusion

Pyrroloquinoline Quinone (PQQ) is a remarkable ingredient with a wide range of benefits for skin care. From its powerful antioxidant and anti-inflammatory properties to its unique ability to support mitochondrial health, PQQ can significantly enhance skin health and appearance. Whether you have dry, sensitive, or aging skin, PQQ could be the ingredient that makes a noticeable difference in your routine. Always remember to consult with a healthcare provider before starting any new supplement and consider taking the Baumann Skin Type quiz to find out if PQQ is a good fit for your skin’s specific needs.

DQH Can I use salicylic acid first and then vitamin C? It’s easy to create a skincare routine, but knowing how to use it is another thing entirely. In most cases, if you’re not getting the desired skin results, it could be due to the layering of conflicting ingredients. So, is it possible that salicylic acid and vitamin C are such ingredients? Or are these active ingredients the duo that’s been missing from your skincare routine? If you want answers, stick around because today we are going to explain the benefits of salicylic acid and vitamin C and how they can be used in your daily life. What are the benefits of salicylic acid for skin? Salicylic acid is one of the most commonly used beta hydroxy acids and is favored by many people with oily, acne-prone skin. This acid is derived from willow bark, and unlike its water-soluble relatives (called alpha-hydroxy acids), salicylic acid is oil-soluble, which means it can penetrate deeper into the lower layers of the skin. Once it reaches the lower layers, it can help unclog pores of excess sebum, dirt, bacteria, debris, and impurities. This results in clearer skin tones and greater definition. Not only does salicylic acid benefit the underlying layers, but the outer surface of the skin benefits as well. When applied to the skin, salicylic acid removes the buildup of dead skin cells. This is accomplished by breaking the bonds that hold dead cells to the surface. Over time, this can cause the complexion to look dull and prone to acne, blackheads, and other blemishes. If you’d like to learn more about salicylic acid and how it can improve your skin, check out this dedicated blog post from a beauty insider. What are the benefits of vitamin C for skin? Vitamin C is considered one of the most powerful antioxidants, which means it is very effective at fighting free radicals and preventing them from causing further skin damage. Examples of free radicals include pollution, central heating, UV rays and harsh climate. They attack proteins, fats and cell membranes as soon as they come into contact with the skin, causing signs of premature aging such as fine lines and wrinkles as well as hyperpigmentation, flaky patches of skin and loss of elasticity. Many people usually prefer to use vitamin C in their morning routine as this ingredient gives the complexion a radiant glow. You’ll also find that vitamin C can target areas of hyperpigmentation, plumping the skin and reducing the appearance of fine lines and wrinkles. The thing about vitamin C is that there are a lot of outdated studies going back to the 1950s that describe vitamin C as an unstable skin component. Thanks to improvements in modern technology, this is no longer the case as all products now contain a stable form of vitamin C. Visit The Beauty Insider to learn more about vitamin C. So please check out our blog post. Can I use salicylic acid first and then vitamin C? Yes, you absolutely can. In fact, it’s thought that using salicylic acid before using vitamin C ensures it penetrates faster and works faster. This is an efficient way to utilize two power sources, and the reason has to do with pH. For example, the skin’s natural pH is about 4.7, making it slightly acidic. Salicylic acid and vitamin C are also both acidic, and you’ll find that vitamin C is absorbed quickly into the skin. Therefore, using salicylic acid beforehand can increase the acidity of the skin and allow vitamin C to penetrate into the skin faster. While this is considered an effective way to combine two powerful ingredients, you need to be aware of your skin type and how it reacts to certain active ingredients. Even people with perfect, normal skin can experience skin sensitivity and irritation. Therefore, always consult a doctor or dermatologist before using any new products on your skin. It’s also important to follow skin application rules. In this case, you need to use the product correctly to ensure you get the best results for your skin. If you’re not sure what I mean, the basic rule for skin is to start with the thinnest consistency and work your way up to the thickest consistency. This prevents a barrier from forming on the surface, preventing other active ingredients from penetrating the skin. Can I use salicylic acid at night and vitamin C in the morning? Yes, absolutely, this is considered the most effective way to get returns without any adverse side effects. This is because there is enough time between applications to ensure that the skin’s pH levels return to balance. You’ll also find that Vitamin C is rich in antioxidants and is perfect for use in the morning to ensure your skin is protected and looking its healthiest. Due to the small size of salicylic acid molecules, it is an acid that is able to reach the deepest parts of the skin. While this is effective at keeping skin clear, it also increases the risk of irritation and photosensitivity. Therefore, many people prefer to use powerful BHAs in their evening routine without exposure to UV rays, pollution, or harsh weather. Warning: If you avoid using sunscreen every day, none of these ingredients will do what your skin needs. The combination of chemical peels and powerful ingredients increases the risk of further damage to the skin’s surface. Use SPF 50 every day to keep your skin protected and your lipid barrier healthy, even on cloudy days, keeping your skin in top condition.

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