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Skin Care Glossary: Dermatologist-Approved Terms for Beginners & Experts
Skin Care

Skin Care Glossary: Dermatologist-Approved Terms for Beginners & Experts

11 May 2025



Skin Care Terms and Vocabulary

You found the best skin care blogs to learn about skin care and a dictionary of skin care terms. We are the top skin care website that has information written by a dermatologist to educate you about skin care science. Whether you are a beginner at skin care, wanting to become an aesthetician, or just want to learn more about how to take care of your skin, you can find the definitions of terms used in skin care here. Look up any terms you need to know about skin care, and click on them to learn more.

You can also search for topics about skin care products and skin conditions in our skin care information library.

To learn about specific skin care ingredients, search in our skin care ingredient library.

You can also learn about skin care by following us on social media @skintypesolutions and watching our educational skin care videos on YouTube.

I’m a dermatologist who is a passionate about skin care. I have written many skin care books including 2 dermatology textbooks. I wrote (and continue writing to keep it current) this skin care library based on information from my bestselling skin care books. (The Skin Type Solution was a NY Times Bestselling Skin Care Book). So if you need to learn the meaning and definitions of words used in skin care- this is the best place to get an education on skin care for beginners.

Where To Learn Skin Care For Beginners

Read through this dictionary of terms to familiarize yourself with skin care terms and skin science words. Then Get started learning in our Skincare 101 blog.

We are so excited that you are ready to learn about skin care with us!

Skin Anatomy:

There are 2 main layers of the skin: The epidermis and the dermis. For details on the skin layers, click here.

Moisturizers affect the epidermis.

To have long lasting results, antiaging skin care ingredients need to be able to penetrate through the epidermis to the dermis.

Basic skin anatomy

Epidermis

The epidermis is the outermost layer of skin. It contains cells called keratinocytes because they make the protein keratin. It is made up of four or five sublayers (depending on the location on the body): the basal layer, spiny layer, granular layer, stratum lucidum, and stratum corneum. Each layer has a different function.

The main role of the epidermis is protection and helping skin stay hydrated.

Dermis

The dermis is the inner most layer of skin, located below the epidermis. It contains specialized skin cells called fibroblasts. This is where important skin components such as collagen, elastin, hyaluronic acid, and heparan sulfate are made. Only a select few topical ingredients are able to reach this layer of skin.

This dermis the skin layer that makes skin look young or old. Wrinkles are caused in the dermis.

Skin Terms for Skin Hydration Anatomy

What is the skin barrier?

Skin Barrier

The skin barrier is located in the stratum corneum, which is the uppermost layer of the epidermis. It is comprised of a lipid bilayer, which retains moisture and prevents allergens and irritants from entering the skin. When the skin barrier is damaged, the skin becomes dry, dehydrated, and susceptible to irritation and inflammation.

Stratum Corneum

The stratum corneum (SC) is the uppermost layer of the epidermis. It used to be called the dead layer of skin cells but we now know it has an important protective role against dehydration and damage from sun, and things that cause skin irritation and skin allergy.

This is where the skin barrier is located. There are 15 to 40 layers of keratinocyte skin cells in the stratum corneum, each arranged like a brick wall. The “mortar” between the skin cell “bricks” is the lipid bilayer (2 rows of fats) that makes up the skin barrier.

This is also the layer that you exfoliate away with facial scrubs and peels.

Kinds of skin cells

Skin Cells

What are skin cells called?

The skin is made up of many types of cells. Keratinocytes are in the epidermis, while fibroblasts are in the dermis. Melanocytes and immune cells move around in the epidermis and dermis.

Melanocyte

Melanocytes are specialized skin cells that produce melanin, the pigment that gives your skin its color. All humans have the same number of melanocytes, but the amount of melanin that these cells produce can vary from person to person which gives us a variety of skin tones. Melanocytes are located in both the epidermis and the dermis. When the melanocytes make too much color, this is called hyperpigmentation. They are stimulated to make color by light, heat, inflammation, hormones, stress, and certain medications.

Keratinocyte

Keratinocytes are the skin cells that make up almost all of the cells located in the epidermis. These cells are created in the basal layer and work their way upward to the epidermis, pushing old skin cells up and out of the way. In the epidermis, the old cells flake off and are replaced by the new keratinocytes. Keratinocytes product the structural protein keratin.

Keratin- the main protein in the epidermis

A structural protein made in the epidermal keratinocytes. Found in the epidermis, hair and nails. This is the substance that clogs pores and causes comedones (Black heads and white heads). The cells in the epidermis make keratin- this is why they are called keratinocytes and the process of cells maturing in the epidermis is called keratinization because each layer of cells in the epidermis makes different kinds of keratin.

Fibroblast

Fibroblasts are specialized cells located in the dermis layer of skin. They are responsible for producing collagen, hyaluronic acid, and elastin. They can move around in the dermis and play an important role in skin thickness, skin aging and wound healing.

hydrophobic vs hydrophilic

Skin Care Product Terms and Vocabulary

Lipophilic-

Stands for “fat loving”. Molecules that are not polar prefer to surround themselves with lipids and repel water. Lipophilic ingredients such as Vitamin E enter the cell membranes and work in these lipid environments while they avoid water environments. It is easier to get lipophilic ingredients into the skin. They are found in moisturizers and oils.

Hydrophilic

Stands for “water loving”. Polar molecules bind water. The interior of the skin cell has water, so hydrophilic ingredients like Vitamin C work inside the cells. Hydrophilic ingredients are found in toners and serums.

categories of skin care ingredients

Ingredient Categories:

Antioxidants

Antioxidants are molecules that donate an electron in order to neutralize harmful free radicals. Antioxidant polyphenols are naturally found in many plants, including berries, green tea, and ginger. Antioxidants in skincare can prevent inflammation, protect skin from pollution, and reduce signs of skin aging.

Anti-inflammatories

Anti-inflammatory ingredients can deactivate one or more of the many inflammatory pathways that lead to inflammation.

Inflammation always has dilated blood vessels (capillaries) which causes skin redness. In some cases of inflammation, the capillaries become leaky and leak water into the surrounding skin causing swelling, This may lead to hives, itching and rashes depending on which inflammatory pathways are turned on.

Skin Lighteners

Skin lighteners are a group of skincare ingredients that even skin tone and lighten skin. They may be called skin brighteners.

They work by one or more of the following ways:

block production of melanin

block transfer of melanosomes from the melanocyte to the keratinocyte

or increase exfoliation

Tyrosinase inhibitors

Tyrosinase is the enzyme necessary to produce the pigment melanin. Tyrosinase inhibitors block this enzyme and prevent the production of melanin. There are many different tyrosinase inhibitors used to treat skin pigmentation problems, such as hydroquinone, resorcinol, vitamin C, arbutin and kojic acid.

PAR-2 blockers

Proteinase-activated receptor 2 (PAR-2) is located in the connection between keratinocytes and melanocytes. It functions as a doorway to allow melanin laden melasomes to enter into the keratinocyte after being produced by melanocytes. PAR-2 blockers prevent melanin from entering keratinocytes. Examples include niacinamide and proteins found in soy.

Exfoliants

The skin’s natural exfoliation process is called desquamation. When natural desquamation is not enough, exfoliants can be used to increase exfoliation. There are two types of exfoliants: chemical and mechanical. Chemical exfoliants use a low pH or enzymes to dissolve and loosen proteins attachments between skin cells. Mechanical exfoliants use friction to rub dead skin cells off of the surface of the skin.

Skin Care Routines

The best way to design a skin care routine is by the Baumann Skin Type. There are 16 Baumann Skin Types based on 4 main skin concerns that need to be considered when building a skin care routine.

The step order of the skin care routine matters.

To learn the basics of skin care routines click here.

To find out your Baumann Skin Type- take the quiz and start learning about your skin’s issues.

Take the Quiz

the right start for your skin care journey

The Right Start For Your Skin Care

Now that you have some basic skin care terminology, browse our skin care library and enjoy going down different rabbit holes of learning. I suggest learning first about your skin type and go from there. Once you take the quiz watch for educational emails that will tell you all about your skin type, what types of products to use, and how to know if they are working.

DQH Can I use salicylic acid first and then vitamin C? It’s easy to create a skincare routine, but knowing how to use it is another thing entirely. In most cases, if you’re not getting the desired skin results, it could be due to the layering of conflicting ingredients. So, is it possible that salicylic acid and vitamin C are such ingredients? Or are these active ingredients the duo that’s been missing from your skincare routine? If you want answers, stick around because today we are going to explain the benefits of salicylic acid and vitamin C and how they can be used in your daily life. What are the benefits of salicylic acid for skin? Salicylic acid is one of the most commonly used beta hydroxy acids and is favored by many people with oily, acne-prone skin. This acid is derived from willow bark, and unlike its water-soluble relatives (called alpha-hydroxy acids), salicylic acid is oil-soluble, which means it can penetrate deeper into the lower layers of the skin. Once it reaches the lower layers, it can help unclog pores of excess sebum, dirt, bacteria, debris, and impurities. This results in clearer skin tones and greater definition. Not only does salicylic acid benefit the underlying layers, but the outer surface of the skin benefits as well. When applied to the skin, salicylic acid removes the buildup of dead skin cells. This is accomplished by breaking the bonds that hold dead cells to the surface. Over time, this can cause the complexion to look dull and prone to acne, blackheads, and other blemishes. If you’d like to learn more about salicylic acid and how it can improve your skin, check out this dedicated blog post from a beauty insider. What are the benefits of vitamin C for skin? Vitamin C is considered one of the most powerful antioxidants, which means it is very effective at fighting free radicals and preventing them from causing further skin damage. Examples of free radicals include pollution, central heating, UV rays and harsh climate. They attack proteins, fats and cell membranes as soon as they come into contact with the skin, causing signs of premature aging such as fine lines and wrinkles as well as hyperpigmentation, flaky patches of skin and loss of elasticity. Many people usually prefer to use vitamin C in their morning routine as this ingredient gives the complexion a radiant glow. You’ll also find that vitamin C can target areas of hyperpigmentation, plumping the skin and reducing the appearance of fine lines and wrinkles. The thing about vitamin C is that there are a lot of outdated studies going back to the 1950s that describe vitamin C as an unstable skin component. Thanks to improvements in modern technology, this is no longer the case as all products now contain a stable form of vitamin C. Visit The Beauty Insider to learn more about vitamin C. So please check out our blog post. Can I use salicylic acid first and then vitamin C? Yes, you absolutely can. In fact, it’s thought that using salicylic acid before using vitamin C ensures it penetrates faster and works faster. This is an efficient way to utilize two power sources, and the reason has to do with pH. For example, the skin’s natural pH is about 4.7, making it slightly acidic. Salicylic acid and vitamin C are also both acidic, and you’ll find that vitamin C is absorbed quickly into the skin. Therefore, using salicylic acid beforehand can increase the acidity of the skin and allow vitamin C to penetrate into the skin faster. While this is considered an effective way to combine two powerful ingredients, you need to be aware of your skin type and how it reacts to certain active ingredients. Even people with perfect, normal skin can experience skin sensitivity and irritation. Therefore, always consult a doctor or dermatologist before using any new products on your skin. It’s also important to follow skin application rules. In this case, you need to use the product correctly to ensure you get the best results for your skin. If you’re not sure what I mean, the basic rule for skin is to start with the thinnest consistency and work your way up to the thickest consistency. This prevents a barrier from forming on the surface, preventing other active ingredients from penetrating the skin. Can I use salicylic acid at night and vitamin C in the morning? Yes, absolutely, this is considered the most effective way to get returns without any adverse side effects. This is because there is enough time between applications to ensure that the skin’s pH levels return to balance. You’ll also find that Vitamin C is rich in antioxidants and is perfect for use in the morning to ensure your skin is protected and looking its healthiest. Due to the small size of salicylic acid molecules, it is an acid that is able to reach the deepest parts of the skin. While this is effective at keeping skin clear, it also increases the risk of irritation and photosensitivity. Therefore, many people prefer to use powerful BHAs in their evening routine without exposure to UV rays, pollution, or harsh weather. Warning: If you avoid using sunscreen every day, none of these ingredients will do what your skin needs. The combination of chemical peels and powerful ingredients increases the risk of further damage to the skin’s surface. Use SPF 50 every day to keep your skin protected and your lipid barrier healthy, even on cloudy days, keeping your skin in top condition.
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