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Can You Safely Combine Vitamin A Serum and Niacinamide in Your Skincare Routine?
Beauty

Can You Safely Combine Vitamin A Serum and Niacinamide in Your Skincare Routine?

28 March 2025


Can You Use Vitamin A Serum and Niacinamide Together?




There are a few ingredients that become a skin dream team when combined in your skincare routine. Niacinamide and vitamin A, also known as retinol, is one duo that can have a positive impact on the overall health and appearance of the skin. Today we will be investigating further into how to use vitamin A serum and niacinamide together, I’m sure you’ll be impressed with the results!



Let’s have a quick recap about each of the ingredients and how they benefit the skin.




What are the benefits of Vitamin A, also known as retinol?



Prevents wrinkles and other signs of ageing developing as well as reducing the appearance of existing fine lines and wrinkles.




Increases the speed of skin cell turnover resulting in the complexion looking vibrant, glowing, and healthy.



Improves the skin texture sloughing away the build-up of dead skin cells and smoothing out the skin.




Helps to regulate sebum production and minimise the frequency of breakouts.



Reduces the appearance of dark spots, sunspots and hyperpigmentation resulting in an even skin tone.




If you wanted to know more about retinol, check out this blog post over on the Beauty Insiders.



What are the benefits of Niacinamide?




Acts as a humectant meaning it is able to draw moisture in from the area surrounding the skin and locking it into the skin. This helps keep the skin plumped, hydrated, and healthy.



Helps to regulate the amount of oil the sebaceous glands produce keeping the skin balanced.




Provides protection from oxidised stress to the skin caused from exposure to free radicals such as smoke, pollution, harsh climates, and other environmental aggressors.



Targets dark spots and hyperpigmentation by lighten the darker areas and increasing collagen production.




Keeps the lipid barrier of the skin at its healthiest state ensuring it can protect itself from environmental stresses.



Minimises the appearance of pores ensuring the pores remain clear and looking less visible over time.




There are more benefits to niacinamide that you can find out more about in our dedicated blog post.



Ok, so now you’ve brushed up on our skincare knowledge, let’s move on to finding out more about using vitamin A and niacinamide together.




What serum can I use with niacinamide?



The beauty of niacinamide is the fact it is versatile and compatible with many skincare ingredients. Even actives as potent as retinol, salicylic acid, and glycolic acid will benefit from a joint application with niacinamide. This is because of the humectant traits enable it to lock moisture into the skin surface. This not only helps keep the lipid barrier healthy but can also counteract the drying effects that can often occur when using such potent ingredients as the ones I have previously mentioned.




You find that there is some confusion around using niacinamide and vitamin C together. This is due to a misconception of teaming both ingredients together because of outdated data. The facts found in the data date back several years when some forms of vitamin C were unstable once blended into formulations. It was considered that applying niacinamide on top would result in a counteractive result on the skin limiting both ingredients to work and deliver their optimal results.



Fast forward to more recent years and this is not the case in a most formulas, but if you still have a concern with layering the ingredients, wait for about ten minutes in between applications to avoid any unwanted side effects.




What can you not mix with niacinamide serum?



As I have already mentioned, niacinamide is an allrounder and effective skincare ingredient. But there is still a little misunderstanding surrounding how to use both niacinamide and vitamin C effectively in your daily routine.




Both ingredients are effective antioxidants and are both found in a great number of skincare products. To get the most out of these actives, there are some dos and don’ts, here are some examples of how many users apply niacinamide and vitamin C.



Ensure when using both ingredients in the same routine that you leave 10 minutes in between applications. This allows the skin’s pH levels to rebalance and prepare for the next ingredient on the skin without the worry of a flare-up or irritation.




Try applying vitamin C in the morning and niacinamide in the evening, this will result in you receiving the benefits of both ingredients and their antioxidant properties. The vitamin C will provide protection throughout the day, and niacinamide will repair any damage that had occurred in your evening routine.



Can I use vitamin A and niacinamide?




Yes, you certainly can use the vitamin A and niacinamide together. Layering the two together helps the skin remain balanced and healthy, whilst benefiting from two powerhouse ingredients delivering impressive results.



Whilst the vitamin A works at rejuvenating the skin, ridding it of dead skin cells, dirt, and bacteria build-up, niacinamide helps to hydrate and counteract the drying effects of retinol. You can choose to use each ingredient separately or combined in one formulation. Whichever you decide to choose I would still recommend consulting with a doctor or dermatologist to ensure these ingredients will be suitable for your skin.




Is vitamin A or niacinamide better?



Although they provide similar benefits to the skin, retinol is much stronger than niacinamide. With this, however, comes some side effects of dryness, irritation, and redness to the skin. It is important to introduce vitamin A (retinol) into your skincare routine to avoid too much irritation to the skin. You’ll also find that it should only be applied to the skin in the evening as exposure to sunlight will result in the powerhouse losing its potency. This is another difference between the two as niacinamide can be used twice a day without any worry of UV rays depleting how effective it is on the skin.




As I have already mentioned, combing both ingredients together are considered a potent skin reviving duo and can be done with ease and peace of mind you won’t be overloading or causing an imbalance to the skin’s pH levels.


There you have a little more information about vitamin A and niacinamide, don’t forget if you had any further questions, you can come and find one of our skincare experts on Instagram.

DQH Can I use salicylic acid first and then vitamin C? It’s easy to create a skincare routine, but knowing how to use it is another thing entirely. In most cases, if you’re not getting the desired skin results, it could be due to the layering of conflicting ingredients. So, is it possible that salicylic acid and vitamin C are such ingredients? Or are these active ingredients the duo that’s been missing from your skincare routine? If you want answers, stick around because today we are going to explain the benefits of salicylic acid and vitamin C and how they can be used in your daily life. What are the benefits of salicylic acid for skin? Salicylic acid is one of the most commonly used beta hydroxy acids and is favored by many people with oily, acne-prone skin. This acid is derived from willow bark, and unlike its water-soluble relatives (called alpha-hydroxy acids), salicylic acid is oil-soluble, which means it can penetrate deeper into the lower layers of the skin. Once it reaches the lower layers, it can help unclog pores of excess sebum, dirt, bacteria, debris, and impurities. This results in clearer skin tones and greater definition. Not only does salicylic acid benefit the underlying layers, but the outer surface of the skin benefits as well. When applied to the skin, salicylic acid removes the buildup of dead skin cells. This is accomplished by breaking the bonds that hold dead cells to the surface. Over time, this can cause the complexion to look dull and prone to acne, blackheads, and other blemishes. If you’d like to learn more about salicylic acid and how it can improve your skin, check out this dedicated blog post from a beauty insider. What are the benefits of vitamin C for skin? Vitamin C is considered one of the most powerful antioxidants, which means it is very effective at fighting free radicals and preventing them from causing further skin damage. Examples of free radicals include pollution, central heating, UV rays and harsh climate. They attack proteins, fats and cell membranes as soon as they come into contact with the skin, causing signs of premature aging such as fine lines and wrinkles as well as hyperpigmentation, flaky patches of skin and loss of elasticity. Many people usually prefer to use vitamin C in their morning routine as this ingredient gives the complexion a radiant glow. You’ll also find that vitamin C can target areas of hyperpigmentation, plumping the skin and reducing the appearance of fine lines and wrinkles. The thing about vitamin C is that there are a lot of outdated studies going back to the 1950s that describe vitamin C as an unstable skin component. Thanks to improvements in modern technology, this is no longer the case as all products now contain a stable form of vitamin C. Visit The Beauty Insider to learn more about vitamin C. So please check out our blog post. Can I use salicylic acid first and then vitamin C? Yes, you absolutely can. In fact, it’s thought that using salicylic acid before using vitamin C ensures it penetrates faster and works faster. This is an efficient way to utilize two power sources, and the reason has to do with pH. For example, the skin’s natural pH is about 4.7, making it slightly acidic. Salicylic acid and vitamin C are also both acidic, and you’ll find that vitamin C is absorbed quickly into the skin. Therefore, using salicylic acid beforehand can increase the acidity of the skin and allow vitamin C to penetrate into the skin faster. While this is considered an effective way to combine two powerful ingredients, you need to be aware of your skin type and how it reacts to certain active ingredients. Even people with perfect, normal skin can experience skin sensitivity and irritation. Therefore, always consult a doctor or dermatologist before using any new products on your skin. It’s also important to follow skin application rules. In this case, you need to use the product correctly to ensure you get the best results for your skin. If you’re not sure what I mean, the basic rule for skin is to start with the thinnest consistency and work your way up to the thickest consistency. This prevents a barrier from forming on the surface, preventing other active ingredients from penetrating the skin. Can I use salicylic acid at night and vitamin C in the morning? Yes, absolutely, this is considered the most effective way to get returns without any adverse side effects. This is because there is enough time between applications to ensure that the skin’s pH levels return to balance. You’ll also find that Vitamin C is rich in antioxidants and is perfect for use in the morning to ensure your skin is protected and looking its healthiest. Due to the small size of salicylic acid molecules, it is an acid that is able to reach the deepest parts of the skin. While this is effective at keeping skin clear, it also increases the risk of irritation and photosensitivity. Therefore, many people prefer to use powerful BHAs in their evening routine without exposure to UV rays, pollution, or harsh weather. Warning: If you avoid using sunscreen every day, none of these ingredients will do what your skin needs. The combination of chemical peels and powerful ingredients increases the risk of further damage to the skin’s surface. Use SPF 50 every day to keep your skin protected and your lipid barrier healthy, even on cloudy days, keeping your skin in top condition.
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